Italian Journal of Medicine 2020-05-28T04:29:37+00:00 Paola Granata Open Journal Systems <p>The <strong>Italian Journal of Medicine (ITJM)</strong> is the official journal of FADOI, the Federation of Associations of Hospital Doctors on Internal Medicine and focus to describe the complex and variable situations confronted by Internists in daily practice. ITJM aims to promote excellence in the practice of internal medicine in hospitals and to disseminate the results of clinical research in internal medicine departments. The journal also contributes to the updating of hospital internists on general topics concerning public health, including ethical, legal, economical and health policy issues. The <strong>Italian Journal of Medicine (ITJM)</strong> is a quarterly peer-reviewed journal aiming to publish highest-quality material covering original basic and clinical research on all aspects of internal medicine. The Journal includes original clinical research papers, reviews, case reports and specific sections dedicated to clinical pharmacology, chronic diseases, health management. The Italian Journal of Medicine is currently indexed in <a title="Scopus" href="" target="_blank" rel="noopener">Scopus</a> and <a title="DOAJ" href="" target="_blank" rel="noopener">DOAJ</a> since September 2009. This journal does not apply the article processing charge&nbsp;to Authors as it is supported by institutional funds.</p> <p><img src="/public/site/images/mikimos/screenshot_7224.png"></p> <p><strong>News</strong></p> <p><strong>The&nbsp;<a href="">XIX Congresso Regionale FADOI Campania, Napoli, 5-6 marzo 2020</a> has been published online (Presidente: M. D'Avino). </strong><em>(27 February 2020)</em></p> <p><img src="/public/site/images/mikimos/screenshot_7224.png"></p> <p>&nbsp;</p> Use of non-invasive ventilation in acute respiratory failure due to SARS-CoV-2 pneumonia: typing of patients and choice of respiratory support, the role of internal medicine 2020-05-28T04:29:37+00:00 Federico Lari Fabrizio Giostra Stefania Guerrini <p>The use of non-invasive ventilation (NIV) during<em> de novo</em> acute hypoxemic respiratory failure is not recommended by the guidelines because NIV does not improve the prognosis. With the advent of the new coronavirus, many cases of acute hypoxemic respiratory failure associated with the infection (severe acute respiratory infection) have been observed: data are missing regarding the use of NIV in this particular clinical condition, but a correct typing of patients based on different clinical, pathophysiological and radiological characteristics, could help in prognostic stratification and in the choice of respiratory support (invasive <em>versus</em> non-invasive). During NIV in these patients particular attention is paid to the possibility of environmental dissemination of the virus and consequently adequate technical precautions are taken.</p> 2020-05-27T06:38:31+00:00 Copyright (c) 2020 the Author(s) Severe paraneoplastic hypoglycemia due to a non-islet cell tumor in a patient with an advanced gastrointestinal stromal tumor 2020-05-27T06:42:50+00:00 Maurizio Alletto Antonio Burgio Giovanni Fulco Giulio Geraci Concetta Groppuso Gianfranco Gruttadauria Elvio Manfrè Gianluca Mastrosimone Susanna Salvaggio Giovanni Urrico Federico Vancheri <p>Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract, mainly localized in the stomach. Most GIST derive from mutations in tyrosine kinase receptors (KIT) or platelet-derived growth factor receptor-α (PDGFRA). GISTs are rarely associated with paraneoplastic hypoglycemia caused by non-β-cells tumor. This syndrome, defined non-islet cell tumor hypoglycemia (NICTH), arises from excess tumor production of insulin-like growth factor. We describe a 67-year-old female with severe NICTH secondary to an advanced and metastatic GIST.</p> 2020-05-19T13:47:03+00:00 Copyright (c) 2020 the Author(s) The new Italian law 219/2017: an extraordinary clinical tool in internal medicine 2020-05-16T04:24:28+00:00 Matteo Bolcato Giacomo Fassina Matteo Sanavio Anna Aprile <p>On December 2017, Law 219 named <em>Provisions for informed consent and advance treatment directives</em> was approved in Italy, and on one side this law helped the daily medical activity on the other side it enhanced the patient's self-determination. This contribution analyzes the new legislative disposition and the possible medical-legal and practical implications for patients entrusted in hospitals. In particular, it focuses on the usefulness of an early planning of medical care decision in complex pathological situations in order to enhance the patient's self-determination and his eventual impassable refusal. It also safeguards the medical work from disputes and claims, preserving medical autonomy and competence.</p> 2020-05-15T09:04:26+00:00 Copyright (c) 2020 the Author(s)