@article{Anzola_Bartolaminelli_Gregorini_Coazzoli_Gatti_Mora_Charalampakis_Palmigiano_De Simone_Comini_Dellaglio_Cassetti_Chiesa_Spedini_d’Ottavi_Savio_2020, title={No harm from angiotensin-converting enzyme inhibitors or angiotensin receptor inhibitors in patients with COVID-19. Results of a prospective study on a hospital-based cohort}, volume={14}, url={https://www.italjmed.org/ijm/article/view/itjm.2020.1313}, DOI={10.4081/itjm.2020.1313}, abstractNote={<p>This study aims to assess the effect of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor inhibitors (ARBs) on the course of COVID-19. It is a prospective study on 221 (M/F ratio= 143/78, mean age 72±13) consecutive hypertensive patients with COVID-19: 76 (34.4%) treated with ACEIs, 63 (28.5%) with ARBs and 82 (37.1%) with antihypertensives OTHER than ACEIs or ARBs. They were all followed up until discharge or death. BAD outcome was defined as the <em>need for invasive mechanical ventilation or death</em>. The three classes of medication were well balanced for confounding variables. BAD outcome was overall recorded in 63/221 (28%) patients, in 20/76 (26%) of ACEI, in 17/63 (27%) of ARB and in 26/82 (32%) of OTHER users, with no statistically significant difference in any comparison. These findings refute the hypothesis that treatment with ACEIs or ARBs may negatively affect the course of COVID-19.</p>}, number={3}, journal={Italian Journal of Medicine}, author={Anzola, Gian Paolo and Bartolaminelli, Clara and Gregorini, Gina Alessandra and Coazzoli, Chiara and Gatti, Francesca and Mora, Alessandra and Charalampakis, Dimitrios and Palmigiano, Andrea and De Simone, Michele and Comini, Alice and Dellaglio, Erica and Cassetti, Salvatore and Chiesa, Maurizio and Spedini, Francesca and d’Ottavi, Patrizia and Savio, Maria Cristina}, year={2020}, month={Sep.}, pages={162–166} }