The challenging diagnosis of intravascular large B-cell lymphoma
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Filipa Coroado Ferreira
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afilipa.csferreira@gmail.com
Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
https://orcid.org/0000-0002-0415-7633
- Tiago Rabadão Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. https://orcid.org/0000-0003-0714-0121
- Leonor Naia Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
- Mariana Teixeira Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
- Marcelo Aveiro Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal.
- Gisela Ferreira Hematology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. https://orcid.org/0000-0003-2812-1448
- Diana Aguiar Internal Medicine Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. https://orcid.org/0000-0002-6052-942X
Abstract
Livedo reticularis (LR) is a net-like cyanotic skin pattern resulting from cutaneous blood flow disturbance associated with several medical conditions. The authors present a case of a 77-year-old woman with a history of asthenia over one year, admitted to the hospital with sepsis by pneumonia. During her hospitalization, she developed a livedoid rash, and skin biopsy revealed infiltrates of atypical mononuclear cells causing capillary lumen obstruction. Intravascular large B-cell lymphoma was suspected and confirmed by bone marrow study. This case highlights the importance of being aware of different medical conditions associated with LR and the atypical presentation of a lymphoproliferative disorder.
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References
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