New-onset type 1 diabetes mellitus triggered by SARS-CoV-2 infection in a patient with Hashimoto thyroiditis: a case report

Abstract

New-onset type 1 diabetes mellitus is an uncommon but possible complication triggered by severe acute respiratory syndrome-related coronavirus 2 infection. Metabolic inflammation supported by cytokine storm leading to pancreatic beta cells destruction is the most probable link between coronavirus disease 2019 (COVID-19) and diabetes. Here, we describe the case of a 51-year-old female suffering from Hashimoto thyroiditis, who came to our attention for new-onset polyuria-polydipsia syndrome associated with hyperglycemia after a mild form of COVID-19 recognized two months before and already recovered. Type 1 diabetes was diagnosed.

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References

Baj J, Karakuła-Juchnowicz H, Teresiński G, et al. COVID-19: specific and non-specific clinical manifestations and symptoms: the current state of knowledge. J Clin Med 2020;9:1753.

Azar WS, Njeim R, Fares AH, et al. COVID-19 and diabetes mellitus: how one pandemic worsens the other [published online ahead of print, 2020 Aug 2]. Rev Endocr Metab Disord 2020;1-13.

Rubino F, Amiel SA, Zimmet P, et al. New-onset diabetes in Covid-19 [published online ahead of print, 2020 Jun 12]. N Engl J Med 2020;10.1056/NEJMc2018688.

Ruggeri RM, Campennì A, Siracusa M, et al. Subacute thyroiditis in a patient infected with SARS-COV-2: an endocrine complication linked to the COVID-19 pandemic [published online ahead of print, 2020 Jul 16]. Hormones (Athens) 2020;1-3.

Bornstein SR, Rubino F, Khunti K, et al. Practical recommendations for the management of diabetes in patients with COVID-19. Lancet Diabetes Endocrinol 2020;8:546-50.

Ye Q, Wang B, Mao J. The pathogenesis and treatment of the ‘Cytokine Storm’ in COVID-19. J Infect 2020;80:607-13.

Marazuela M, Giustina A, Puig-Domingo M. Endocrine and metabolic aspects of the COVID-19 pandemic [published online ahead of print, 2020 Jul 9]. Rev Endocr Metab Disord 2020;1-13.

Bellastella G, Maiorino MI, Esposito K. Endocrine complications of COVID-19: what happens to the thyroid and adrenal glands?. J Endocrinol Invest 2020;43:1169-70.

Heaney AI, Griffin GD, Simon EL. Newly diagnosed diabetes and diabetic ketoacidosis precipitated by COVID-19 infection [published online ahead of print, 2020 Jun 6]. Am J Emerg Med 2020;S0735-6757(20)30488-5.

Marchand L, Pecquet M, Luyton C. Type 1 diabetes onset triggered by COVID-19 [published online ahead of print, 2020 Jul 11]. Acta Diabetol 2020;1-2.

Chee YJ, Ng SJH, Yeoh E. Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus. Diabetes Res Clin Pract 2020;164:108166.

Published
2021-01-25
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Issue
Section
Case Reports
Keywords:
Diabetes, SARS-CoV-2, COVID-19, hyperglycemia, glutamic acid decarboxylase-65 autoantibodies.
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How to Cite
Schipani, E., Cozzi, A., Murgida, G. S., Francolini, V., Sisti, E., Di Martino, S., Dainelli, F., Vecchio, R., Grifoni, E., & Masotti, L. (2021). New-onset type 1 diabetes mellitus triggered by SARS-CoV-2 infection in a patient with Hashimoto thyroiditis: a case report. Italian Journal of Medicine, 15(1). https://doi.org/10.4081/itjm.2021.1387