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Transient global amnesia: an uncommon presentation of acute myocardial infarction

Paolo Tirelli, Fulvio Cacciapuoti, Filomena Scarano, Federico Cacciapuoti
  • Paolo Tirelli
    Department of Internal Medicine, S. Maria di Loreto Nuovo Hospital, Naples, Italy
  • Fulvio Cacciapuoti
    Emergency Department, A. Cardarelli Hospital, Naples, Italy
  • Filomena Scarano
    Department of Internal Medicine, L. Vanvitelli University, Naples, Italy


Transient global amnesia (TGA) is an acute neurological syndrome characterized by sudden-onset global (anterograde and retrograde) amnesia, without compromising other neurological functions. This clinical condition lasts up to 24 h with whole restoration. Several causes have been proposed as responsible for it. Among these, acute myocardial infarction (AMI) was reported as a rare cause of TGA. Sympathetic hyperactivity occurring too early in AMI seems to induce vasospasm, responsible for venous cerebral congestion acting on hippocampal and temporal structures and consequent memory loss. A rare case of TGA as precocious display of subsequent AMI was described.


Transient global amnesia; hippocampus; memory loss; acute myocardial infarction; sympathetic hyperactivity.

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Submitted: 2017-11-07 18:49:24
Published: 2018-06-20 12:31:21
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Copyright (c) 2018 Paolo Tirelli, Fulvio Cacciapuoti, Filomena Scarano, Federico Cacciapuoti

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