The impact of saffron (Crocus sativus) supplementation on visual function in patients with dry age-related macular degeneration

  • Abbas Riazi Department of Ophthalmology, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Yunes Panahi | yunespanahi@yahoo.com Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Ali A. Alishiri Department of Ophthalmology, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Mohammad A. Hosseini Department of Ophthalmology, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Ali A. Karimi Zarchi Department of Epidemiology and Biostatics, Baqiyatallah University of Medical Sciences, Tehran, Iran, Islamic Republic of.
  • Amirhossein Sahebkar Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, Islamic Republic of.

Abstract

The aim was to evaluate the impact of saffron supplementation on visual function in patients with dry age-related macular degeneration (ARMD). Fifty-four participants, 23 males and 31 females, with dry ARMD were assigned to one of the following two groups. The treatment group (n=29) consumed 50 mg saffron daily during a 3-month period, while 25 subjects served as the control group. Visual acuity, contrast sensitivity, and retinal thickness were measured at the beginning and at the end of the study. Quality of life was evaluated using the Melbourne low vision index before and after treatment. Significant increases in visual acuity and contrast sensitivity were found in the saffron group but not in the control group. Changes in macular thickness were not statistically different between the two groups. Short-term consumption of saffron may slow down the progression of disease and improve visual function, especially contrast sensitivity, in patients with dry ARMD.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2016-08-11
Info
Issue
Section
Original Articles
Keywords:
Saffron, age-related macular degeneration, visual acuity, contrast sensitivity, macular thickness.
Statistics
  • Abstract views: 2003

  • PDF: 878
  • HTML: 592
How to Cite
Riazi, A., Panahi, Y., Alishiri, A. A., Hosseini, M. A., Karimi Zarchi, A. A., & Sahebkar, A. (2016). The impact of saffron (Crocus sativus) supplementation on visual function in patients with dry age-related macular degeneration. Italian Journal of Medicine, 11(2), 196-201. https://doi.org/10.4081/itjm.2016.758

Most read articles by the same author(s)