Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management | Italian Journal of Medicine

DOI https://doi.org/10.4081/itjm.2015.547

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Published: Dec 15, 2015

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Issue

Vol 9, No 4 (2015)

Pages

330-345

Keywords

Primary hyperparathyroidism, parathyroidectomy, hypercalcemic status.

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Percivale, A., Gnerre, P., Damonte, G., Buscaglia, S., Monachesi, M., Parodi, L., Tassara, R., Curletti, G., & Saccomani, G. (2015). Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management. Italian Journal of Medicine, 9(4), 330-345. https://doi.org/10.4081/itjm.2015.547

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Andrea Percivale

Department of Surgery, Santa Corona Hospital, Pietra Ligure (SV), Italy.

Paola Gnerre *

Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Giulio Damonte

Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Sandra Buscaglia

Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Mario Monachesi

Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Lionello Parodi

Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Rodolfo Tassara

Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Gianluca Curletti

Department of Surgery, University of Genova, Genova, Italy.

Giovanni Saccomani

Department of Surgery, Santa Corona Hospital, Pietra Ligure (SV), Italy.

(*) Corresponding Author:
Paola Gnerre |

pgnerre@yahoo.it

Abstract

Primary hyperparathyroidism (PHPT) is a clinical condition characterized by overactive parathyroid gland secretion of parathyroid hormone with concurrent alteration of the phosphocalcemic metabolism. We present a literature review on primary hyperparathyroidism addressing key on clinical presentation, causes, medical and surgical treatment at the best of our knowledge. Based on this review we confirm the role of serum calcium and serum level examination, as well as we define the definitive treatment for PHPT being parathyroidectomy. In case of contraindication for surgery, medical treatment can play a relevant role.

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