Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management

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Andrea Percivale
Paola Gnerre *
Giulio Damonte
Sandra Buscaglia
Mario Monachesi
Lionello Parodi
Rodolfo Tassara
Gianluca Curletti
Giovanni Saccomani
(*) Corresponding Author:
Paola Gnerre |


Primary hyperparathyroidism (PHPT) is a clinical condition characterized by overactive parathyroid gland secretion of parathyroid hormone with concurrent alteration of the phosphocalcemic metabolism. We present a literature review on primary hyperparathyroidism addressing key on clinical presentation, causes, medical and surgical treatment at the best of our knowledge. Based on this review we confirm the role of serum calcium and serum level examination, as well as we define the definitive treatment for PHPT being parathyroidectomy. In case of contraindication for surgery, medical treatment can play a relevant role.

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