Reviews
Vol. 9 No. 4 (2015)
https://doi.org/10.4081/itjm.2015.547

Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management

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Received: 3 October 2014
Published: 15 December 2015
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Primary hyperparathyroidism, parathyroidectomy, hypercalcemic status.

Authors

Andrea Percivale
Department of Surgery, Santa Corona Hospital, Pietra Ligure (SV), Italy.
Paola Gnerre
pgnerre@yahoo.it
Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
Giulio Damonte
Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
Sandra Buscaglia
Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
Mario Monachesi
Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
Lionello Parodi
Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
Rodolfo Tassara
Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
Gianluca Curletti
Department of Surgery, University of Genova, Genova, Italy.
Giovanni Saccomani
Department of Surgery, Santa Corona Hospital, Pietra Ligure (SV), Italy.
Primary hyperparathyroidism (PHPT) is a clinical condition characterized by overactive parathyroid gland secretion of parathyroid hormone with concurrent alteration of the phosphocalcemic metabolism. We present a literature review on primary hyperparathyroidism addressing key on clinical presentation, causes, medical and surgical treatment at the best of our knowledge. Based on this review we confirm the role of serum calcium and serum level examination, as well as we define the definitive treatment for PHPT being parathyroidectomy. In case of contraindication for surgery, medical treatment can play a relevant role.

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Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management. (2015). Italian Journal of Medicine, 9(4), 330-345. https://doi.org/10.4081/itjm.2015.547

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