Complexity of patients with chronic obstructive pulmonary disease hospitalized in internal medicine: a survey by FADOI

  • Carlo Nozzoli Department of Internal Medicine, AOU Careggi, Florence, Italy.
  • Luigi Anastasio Internal Medicine, Jazzolino Hospital, Vibo Valentia, Italy.
  • Leonardo M. Fabbri Oncology Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy.
  • Pietro Marino Emergency Medicine, Fatebenefratelli Hospital, Milan, Italy.
  • Roberto Nardi | Internal Medicine C, Maggiore Hospital, Bologna, Italy.
  • Antonio Sacchetta Internal Medicine, Hospital of Conegliano Veneto (TV), Italy.
  • Franco Mastroianni Internal Medicine, F. Miulli Hospital, Acquaviva delle Fonti (BA), Italy.
  • Giovanni Mangano Internal Medicine, Fatebenefratelli Hospital, Palermo, Italy.
  • Fabrizio Lombardini Internal Medicine, S.S. Trinità Hospital, Cagliari, Italy.
  • Angela Zappaterra Internal Medicine, S. Chiara Hospital, Trento, Italy.
  • Antonella Valerio Research Department, FADOI Foundation, Milan, Italy.
  • Giorgio Vescovo Internal Medicine, San Bortolo Hospital, Vicenza, Italy.
  • Giancarlo Agnelli Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy.
  • Mauro Campanini Department of Internal Medicine, Maggiore della Carità Hospital, Novara, Italy.
  • for the Research Department of FADOI


Chronic obstructive pulmonary disease (COPD) is one of the most frequent pathologies among patients hospitalized in Internal Medicine (IM) Departments. COPD is frequently associated with concomitant diseases, which represent major causes of death, and affect disease management. Objectives of our study are to assess the prevalence of COPD patients in IM, to evaluate their comorbidity status, and to describe their complexity, by means of the validated multidimensional prognostic index (MPI) score. COMPLEXICO is an observational, prospective, multicenter study, enrolling consecutive patients hospitalized for any cause in IM, with diagnosis of COPD documented by spirometry. A total of 1002 patients in 43 IM Units in Italy were enrolled. The prevalence of COPD in IM was found to be 18.1%, and 72.8% of patients had at least three chronic diseases other than COPD. The mean MPI was 0.43±0.15, and according to a stratification algorithm 31.8% of patients were classified as having low-risk, 58.9% moderate-risk and 9.3% severe-risk of adverse outcome. More than two-thirds of COPD patients in our study present moderate to severe risk of poor outcome according to the MPI stratification.



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FADOI Position Statement
Internal medicine, complexity, chronic obstructive pulmonary disease, multidimensional prognostic index.
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How to Cite
Nozzoli, C., Anastasio, L., Fabbri, L. M., Marino, P., Nardi, R., Sacchetta, A., Mastroianni, F., Mangano, G., Lombardini, F., Zappaterra, A., Valerio, A., Vescovo, G., Agnelli, G., Campanini, M., & of FADOI, for the R. D. (2015). Complexity of patients with chronic obstructive pulmonary disease hospitalized in internal medicine: a survey by FADOI. Italian Journal of Medicine, 9(2), 120-124.

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