Carbapenemase-producing Klebsiella pneumoniae in elderly frail patients admitted to medical wards

  • Antonio Nouvenne | antonio.nouvenne@alice.it Department of Clinical and Experimental Medicine, University of Parma, Italy.
  • Andrea Ticinesi Department of Clinical and Experimental Medicine, University of Parma, Italy.
  • Tiziana Meschi Department of Clinical and Experimental Medicine, University of Parma, Italy.

Abstract

Carbapenemase-producing Klebsiella pneumoniae (CPKP) is rapidly emerging as a leading nosocomial infection in many countries, especially in Italy where it is considered endemic. In this paper we briefly summarize the main characteristics of this outbreak, focusing on its recent spread to elderly frail patients admitted to internal medicine and geriatric wards. Severity of disease, clinical complexity and a large number of comorbidities seem to be major risk factors in clinical practice, although scientific evidence is still lacking, since until now studies have been carried out mainly in intensive care settings. We also discuss the possible role of gut microbiota in CPKP colonization onset and the possible role of pre-probiotics in promoting eradication.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2014-02-04
Info
Issue
Section
Reviews
Keywords:
Carbapenemases, Klebsiella pneumoniae, elderly patients, comorbidities, gut microbiota.
Statistics
  • Abstract views: 1460

  • PDF: 950
  • HTML: 318
How to Cite
Nouvenne, A., Ticinesi, A., & Meschi, T. (2014). Carbapenemase-producing Klebsiella pneumoniae in elderly frail patients admitted to medical wards. Italian Journal of Medicine, 9(2), 116-119. https://doi.org/10.4081/itjm.2014.476