https://doi.org/10.4081/itjm.2023.1676
The pharmacological deprescription in elderly patients
Published: 19 December 2023
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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The demographic of individuals aged 65 and above represents one of the fastest-growing populations globally. As of 2020, there were 727 million individuals (9.3%) aged 65 years or older worldwide. Projections indicate that the number of older adults will double to reach 1.5 billion (16%) by 2050.1 At that point, 1 in 6 people globally will be over 65, and in Europe and North America, 1 in 4 individuals may fall into this age bracket. [...]
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Citations
United Nations. Department Of Economic And Social Affairs. Population Division. World Population Ageing 2020 Highlights: Living Arrangements of Older Persons. United Nations, 2020.
Nations U. Ageing. United Nations. Available from: https://www.un.org/en/global-issues/ageing#:~:text=Trends%20in%20Population%20Ageing
United Nations. Department Of Economic And Social Affairs. Population Division. World Population Ageing, 2019 Highlights. New York: United Nations, 2019. Available from: https://www.un.org/en/development/desa/population/ publications/pdf/ageing/WorldPopulationAgeing2019-Highlights.pdf
Onder G, Vetrano DL, Cherubini A, et al. Prescription drug use among older adults in Italy: a country-wide perspective. J Am Med Dir Assoc 2014;15:531.e11-531.e15.
DOI: https://doi.org/10.1016/j.jamda.2014.04.005
Ricciardi W, Tarricone R. The evolution of the Italian National Health Service. The Lancet. Published online October 22, 2021.
DOI: https://doi.org/10.1016/S0140-6736(21)01733-5
The Elderly: health conditions in Italy and in the European Union. 2017. Available from: https://www.istat.it/en/ archive/203827 (accessed November 15, 2023)
Halli-Tierney AD, Scarbrough C, Carroll D. Polypharmacy: Evaluating Risks and Deprescribing. American Family Physician 2019;100:32-8.
Sinha A, Mukherjee S, Tripathi S, Dutta S. Issues and challenges of polypharmacy in the elderly: A review of contemporary Indian literature. J Family Med Prim Care 2021;10:3544.
DOI: https://doi.org/10.4103/jfmpc.jfmpc_2581_20
Thomas RB, Jang SR, Lombardi M, Maio V. The prescription paradox: a guide to appropriate prescribing in the elderly. Geriatr Care 2019;5.
DOI: https://doi.org/10.4081/gc.2019.8523
Sultana J, Elisabetta Poluzzi, Lunghi C, et al. Deprescribing as a strategy for improving safety of medicines in older people: Clinical and regulatory perspective. Frontiers 2022;2.
DOI: https://doi.org/10.3389/fdsfr.2022.1011701
Scott IA, Hilmer SN, Reeve E, et al. Reducing inappropriate polypharmacy: the process of deprescribing. JAMA Intern Med.2015;175:827-34.
DOI: https://doi.org/10.1001/jamainternmed.2015.0324
Reeve E, Moriarty F, Nahas R, et al. A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms. Expert Opin Drug Saf 2018;17:39-49.
DOI: https://doi.org/10.1080/14740338.2018.1397625
Niriayo YL, Kumela K, Kassa TD, Angamo MT. Drug therapy problems and contributing factors in the management of heart failure patients in Jimma University Specialized Hospital, Southwest Ethiopia. PLoS One 2018;13:e0206120.
DOI: https://doi.org/10.1371/journal.pone.0206120
Sternberg SA, Guy-Alfandary S, Rochon PA. Prescribing cascades in older adults. CMAJ 2021;193:E215.
DOI: https://doi.org/10.1503/cmaj.201564
Bain KT, Holmes HM, Beers MH, et al. Discontinuing medications: a novel approach for revising the prescribing stage of the medication-use process. J Am Geriatr Soc 2008;56:1946-52.
DOI: https://doi.org/10.1111/j.1532-5415.2008.01916.x
Deprescribing resources. Primary Health Tasmania. Available from: https://www.primaryhealthtas.com.au/resources/deprescribing-resources/
Deprescribing algorithms. Do I still need this medication? Is deprescribing for you? Available from: https://www.deprescribingnetwork.ca/algorithms
Zarowitz B, Brandt N. Deprescribing In Assisted Living. Innov Aging 2022;6:250.
DOI: https://doi.org/10.1093/geroni/igac059.993
Barnett N, Kelly O. Deprescribing: is the law on your side? Eur J Hosp Pharma 2016;24:21-5.
DOI: https://doi.org/10.1136/ejhpharm-2016-000949
Barnett N, Kelly Ó. Legal implications of deprescribing: a case scenario. Prescriber 2017;28:49-52.
DOI: https://doi.org/10.1002/psb.1552
Budd J. Burnout Related to Electronic Health Record Use in Primary Care. J Prim Care Community Health. 2023;14:21501319231166921.
DOI: https://doi.org/10.1177/21501319231166921
EHR Poll Results. EHR National Symposium. Available from: https://www.med.stanford.edu/ehr/electronichealth-records-poll-results.html
Smith CD, Balatbat C, Corbridge S, et al. Implementing Optimal Team-Based Care to Reduce Clinician Burnout. NAM Perspectives. 2018;8.
DOI: https://doi.org/10.31478/201809c
Lawry T. AI in Health: A Leader’s Guide to Winning in the New Age of Intelligent Health Systems. CRC Press, Taylor & Francis Group, 2020.
DOI: https://doi.org/10.4324/9780429321214
Lawry T. The future of AI in medicine and what it means for physicians and practices with Tom Lawry. American Medical Association, 2023. Available from: https://www.ama-assn.org/practice-management/digital/futureai-medicine-and-what-it-means-physicians-and-practicestom-lawry
Fajardo MA, Weir KR, Bonner C, et al. Availability and readability of patient education materials for deprescribing: An environmental scan. Br J Clin Pharmacol 2019;85:1396-406.
DOI: https://doi.org/10.1111/bcp.13912
Patient handouts. Do I still need this medication? Is deprescribing for you? Available from: https://www.deprescribingnetwork.ca/patient-handouts
Farrell B, Mangin D. Deprescribing Is an Essential Part of Good Prescribing. Am Fam Physician 2019;99:7-9.
Baile WF, Buckman R, Lenzi R, et al. SPIKES-A six-step protocol for delivering bad news: application to the patient with cancer. Oncologist 2000;5:302-11.
DOI: https://doi.org/10.1634/theoncologist.5-4-302
Rabow MW, McPhee SJ. Beyond breaking bad news: how to help patients who suffer. West J Med 1999;171:260-3.
Clayton JM, Hancock KM, Butow PN, et al. Clinical practice guidelines for communicating prognosis and end-of-life issues with adults in the advanced stages of a life-limiting illness, and their caregivers. Med J Aust 2007;186:S77-S105.
DOI: https://doi.org/10.5694/j.1326-5377.2007.tb01100.x
Kaufmann CP, Tremp R, Hersberger KE, et al. Inappropriate prescribing: a systematic overview of published assessment tools. Eur J Clin Pharmacol 2014;70:1-11.
DOI: https://doi.org/10.1007/s00228-013-1575-8
AUSL, Azienda. Available from: https://www.ausl.pr.it/azienda/appropriatezza_prescrittiva/default.aspx (accessed November 15, 2023)
Vaffis S, Dhatt H, Anderson EJ, et al. A checklist for a consistent, comprehensive medication review. J Am Pharma Associ 2023;63:1504-7.e1.
DOI: https://doi.org/10.1016/j.japh.2023.06.020
How to Cite
Ali, C., Huang, D., Tugwete, C., Del Canale, S., & Maio, V. (2023). The pharmacological deprescription in elderly patients. Italian Journal of Medicine, 17(3). https://doi.org/10.4081/itjm.2023.1676
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