https://doi.org/10.4081/itjm.2024.1670
Medicinal potential of antimicrobial peptides from two plants against Bacillus cereus and Staphylococcus aureus
Submitted: 24 November 2023
Accepted: 29 December 2023
Published: 1 February 2024
Accepted: 29 December 2023
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Bacillus cereus and Staphylococcus aureus are the most important bacteria that cause nosocomial infection and are resistant to antibiotics. Crude proteins from Cassia fistula and Ricinus communis were isolated to study their medicinal potential against Bacillus cereus, and Staphylococcus aureus. Extraction of the crude proteins from plants was done by phosphate buffer saline (PBS) and Tris NaCl buffer by using the roots and seeds of both plants. Antimicrobial activity was checked against bacterial strains by using agar disc diffusion and agar well diffusion methods. Zones of inhibitions were measured. On well diffusion method, PBS buffer protein extract of C. fistula roots showed a maximum zone of inhibition of 25 mm against B. cereus. Tris NaCl buffer extracts of C. fistula roots and seeds showed zones of inhibition of 12mm and 5mm respectively against S. aureus while Ricinus communis roots showed a zone of 12mm against B. cereus. Because the protein of the plants showed good antimicrobial activity, we can use these plants against various diseases caused by Bacillus cereus and Staphylococcus aureus.
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How to Cite
Jabeen, R., Javed, E., Habiba, U., Choohan, M. A., Asim, M., Alatawi, F. S., Ishfaq , H., & Nisar, J. (2024). Medicinal potential of antimicrobial peptides from two plants against <i>Bacillus cereus</i> and <i>Staphylococcus aureus</i>. Italian Journal of Medicine, 18(1). https://doi.org/10.4081/itjm.2024.1670
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