https://doi.org/10.4081/itjm.2023.1603

Lung damages of malaria: a differential diagnosis and treatment in emergency room of a rare case

Vol. 17 No. 3 (2023)
Published: 29 November 2023
Pneumonia, malaria, pulmonary manifestations, corticosteroids
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Authors

Novella Carannante
carannantenovella@gmail.com
Emergency Room Cotugno Hospital AO dei Colli, Naples, Italy.
Sabrina Scarica
https://orcid.org/0000-0002-4928-9840
Emergency Room Cotugno Hospital AO dei Colli, Naples, Italy.
Raffaele Disarno
Emergency Room Cotugno Hospital AO dei Colli, Naples, Italy.
Gerardo Langella
Phisiophatology Respiratory Monaldi Hospital, AO dei Colli Naples, Italy.
Pierpaolo Di Micco
AFO Medicina, PO Santa Maria delle Grazie, ASL Napoli 2 nord, Pozzuoli (NA), Italy.
Giuseppe Fiorentino
https://orcid.org/0000-0002-2523-9769
Phisiophatology Respiratory Monaldi Hospital, AO dei Colli Naples, Italy.

Pulmonary involvement occurs in 3 to 10% of the cases of Plasmodium falciparum malaria and represents the most severe complication of this infection, with a lethality of about 70%. The antigens released by the parasite play an important role in the induction and worsening of lung damage. Capillary endothelial cells, which control the flux of fluids to the interstitial space, appear to be the most complicated structures. The clinical manifestations of pulmonary involvement may start suddenly at any time during the course of malaria, even after the disappearance of the circulating parasite. Hyperparasitemia predisposes to these factors. Treatment with corticosteroids is optional, and that is not often a benefit.

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No financial support was necessary for the conduct of this study. None of the authors have conflicts of interest.

How to Cite

Carannante, N., Scarica, S., Disarno, R., Langella, G., Di Micco, P., & Fiorentino, G. (2023). Lung damages of malaria: a differential diagnosis and treatment in emergency room of a rare case. Italian Journal of Medicine, 17(3). https://doi.org/10.4081/itjm.2023.1603
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