https://doi.org/10.4081/itjm.2021.1378

Gender differences in ischemic stroke intra-hospital mortality: a systematic review

Vol. 15 No. 2 (2021)
Submitted: 27 September 2020
Accepted: 30 December 2020
Published: 30 June 2021
Mortality, ischemic stroke, gender/sex differences, not hemorrhagic stroke.
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Authors

Tiziana Ciarambino
tiziana.ciarambino@gmail.com
Internal Medicine Department, Hospital of Marcianise, ASL Caserta, Italy.
Orazio Valerio Giannico
Dipartimento di Prevenzione, ASL Taranto, Italy.
Amalia Campanile
Department of Internal Medicine, University of Campania L. Vanvitelli, Naples, Italy.
Antonella Fischetti
Department of Internal Medicine, University of Campania L. Vanvitelli, Naples, Italy.
Elena Barabgelata
Department of Internal Medicine, Lavagna Hospital, Genova, Italy.
Imma Ambrosino
Local Healthcare Unit of Bari, Health District 10, Post-acute Care Triggiano, Bari, Italy.
Ombretta Para
Internal Medicine Department, Ospedale Careggi, University of Florence, Florence, Italy.
Cecilia Politi
Head of Gender Medicine Area FADOI, Internal Medicine Department, Isernia, Italy.
Mauro Giordano
Department of Internal Medicine, University of Campania L. Vanvitelli, Naples, Italy.

The aim was to evaluate whether intra-hospital mortality from ischemic stroke is different in female patients. Methods. Studies were found in PubMed, Web of Science. We excluded 119 records because they did not include relevant reports or data. Studies were eligible for inclusion if enrolled adult patients with ischemic stroke and if the odds ratio (OR) of intra-hospital mortality in females compared to males is provided. Three retrospective cohort studies were eligible for inclusion criteria and so were included in the analysis. Findings: the random effect model showed a pooled significant higher risk of intra-hospital mortality [OR 1.34 (95% confidence interval 1.04, 1.74), P=0.026] in the female group compared to the male group. Our systematic review shows that intra-hospital mortality was significantly higher in female subjects compared to male.

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How to Cite

Ciarambino, T., Giannico, O. V., Campanile, A., Fischetti, A., Barabgelata, E., Ambrosino, I., Para, O., Politi, C., & Giordano, M. (2021). Gender differences in ischemic stroke intra-hospital mortality: a systematic review. Italian Journal of Medicine, 15(2). https://doi.org/10.4081/itjm.2021.1378
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