https://doi.org/10.4081/itjm.2021.1350

HIV, HCV and SARS-CoV-2: friends or foes? A case report

Vol. 15 No. 3 (2021)
Submitted: 30 July 2020
Accepted: 9 February 2021
Published: 24 September 2021
SARS-CoV-2, HCV, HIV, co-infection, Italy.
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Authors

Elena Garlatti Costa
https://orcid.org/0000-0002-7817-5607
Department of Internal Medicine, ASFO, Azienda Sanitaria Friuli Occidentale, Ospedale Santa Maria degli Angeli, Pordenone, Italy.
Cesare Mazzaro
cesare.mazzaro@gmail.com
https://orcid.org/0000-0002-0305-6574
Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico (CRO) Aviano, IRCCS, Aviano (PN), Italy.
Alessandro Grembiale
https://orcid.org/0000-0002-2527-0010
Department of Internal Medicine, ASFO, Azienda Sanitaria Friuli Occidentale, Ospedale Santa Maria degli Angeli, Pordenone, Italy.
Alessandro Berto
https://orcid.org/0000-0003-4454-1274
Department of Microbiology and Virology, ASFO, Azienda Sanitaria Friuli Occidentale, Ospedale Santa Maria degli Angeli, Pordenone, Italy.
Rita De Rosa
Department of Microbiology and Virology, ASFO, Azienda Sanitaria Friuli Occidentale, Ospedale Santa Maria degli Angeli, Pordenone, Italy.
Silvia Grazioli
Department of Internal Medicine, ASFO, Azienda Sanitaria Friuli Occidentale, Ospedale Santa Maria degli Angeli, Pordenone, Italy.
Maurizio Tonizzo
Department of Internal Medicine, ASFO, Azienda Sanitaria Friuli Occidentale, Ospedale Santa Maria degli Angeli, Pordenone, Italy.

Data about co-infection of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), HIV, and hepatitis C virus (HCV) are still scarce. We describe a patient hospitalized for sore throat, fatigue, and myalgia with a personal history of HIV and occult HBV infection. His antiretroviral therapy included bictegravir/emtricitabine/tenofovir alafenamide. The nasopharyngeal swab was positive for SARS-CoV-2 and laboratory testing showed acute HCV. Antiretroviral therapy was continued, but no specific therapy for SARS-CoV-2 was started. After 4 weeks, the nasopharyngeal swab resulted negative for SARS-CoV-2 and biochemical tests revealed undetectable HCV RNA with normalization of transaminases. To the best of our knowledge, this is the first reported case of acute HCV in a patient with HIV and SARS-CoV-2 co-infection.

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How to Cite

Garlatti Costa, E. ., Mazzaro, C., Grembiale, A., Berto, A., De Rosa, R. ., Grazioli, S., & Tonizzo, M. (2021). HIV, HCV and SARS-CoV-2: friends or foes? A case report. Italian Journal of Medicine, 15(3). https://doi.org/10.4081/itjm.2021.1350
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