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The Italian Journal of Medicine (ITJM) is the official journal of FADOI, the Federation of Associations of Hospital Doctors on Internal Medicine and focus to describe the complex and variable situations confronted by Internists in daily practice. ITJM aims to promote excellence in the practice of internal medicine in hospitals and to disseminate the results of clinical research in internal medicine departments. The journal also contributes to the updating of hospital internists on general topics concerning public health, including ethical, legal, economical and health policy issues. ITJM is a quarterly peer-reviewed journal aiming to publish highest-quality material covering original basic and clinical research on all aspects of internal medicine. The Journal includes original clinical research papers, reviews, case reports and specific sections dedicated to clinical pharmacology, chronic diseases, health management. ITJM is currently indexed in Web of Science/ESCI, Scopus and DOAJ since September 2009.

New Articles

  • Evaluation of the renal function among sickle cell patients: a cross-sectional study

    Talal Qadah, Anwar Refaei
    https://doi.org/10.4081/itjm.2025.1868
    38
    PDF: 15
    SUPPLEMENTARY MATERIAL: 5

  • Virus-induced asthma exacerbations in Vietnamese preschoolers

    Nguyen Thuy Van Thao, Tran Anh Tuan, Pham Hung Van, Le Thuong Vu
    https://doi.org/10.4081/itjm.2025.1818
    36
    PDF: 16

  • Acute kidney failure due to varicella-zoster virus solved by early antiviral treatment based on brivudin

    Fulvia Paolozzi, Pierpaolo Di Micco, Antonella Giliberti, Gianluca Latte, Maria Teresa Feola, Immacolata Gaia Paduano, Concetta Schiano, Maurizio Latte
    https://doi.org/10.4081/itjm.2025.1786
    95
    PDF: 66

  • Serum transferrin level in type-2 diabetic patients in association with sociodemographic profile and dietary habits

    Anza Khan, Uzma Rafi, Riffat Mehboob, Sajid Hameed, Uzma Malik, Zainab Zubair, Imran Shahid
    https://doi.org/10.4081/itjm.2025.1873
    125
    PDF: 91
    HTML: 0

  • An algorithm for the management of chronic obstructive pulmonary disease patients in units of internal medicine

    Ombretta Para, Carmen Stabile, Donato Cinquepalmi, Maria Sandra Magnoni, Francesco Nasso, Flavio Tangianu, Mauro Silingardi, Antonella Valerio, Dario Manfellotto, Francesco Dentali
    https://doi.org/10.4081/itjm.2025.1838
    219
    PDF: 544
    HTML: 1

  • The unseen connection: laryngeal carcinoma and thrombosis of the internal jugular vein

    Laura Leci-Tahiri, Lisa Tahiri, Valbona Zhjeqi, Emina Ramku
    https://doi.org/10.4081/itjm.2025.1882
    1507
    PDF: 39
    HTML: 1

  • The incidence of bleeding in patients with nonvalvular atrial fibrillation using anticoagulants: a real-world report with the biggest Vietnamese data

    Bui The Dung, Cao Ngoc Mai Han, Tran Hoa, Nguyen Thanh Hien
    https://doi.org/10.4081/itjm.2025.1807
    1528
    PDF: 45
    HTML: 0

  • Predictive value of Frank’s sign for obstructive coronary artery disease confirmed by coronary computed tomography angiography

    Truong Phi Hung, Nguyen Minh Kha, Dang Tuong Vi, Tran Trong Nhan, Hoang Van Sy
    https://doi.org/10.4081/itjm.2025.1863
    1471
    PDF: 123
    SUPPLEMENTARY MATERIAL: 29
    HTML: 1

  • First evidence of immunomodulation of the renin-angiotensin system through substance P/neurokinin 1 receptor: a case and control study in hypertension and cardiac patients

    Ibrahim M. Alanazi, Riffat Mehboob, Ayesha Tariq, Sajid Hameed, Uzma Malik, Noreen Sarwar, Imran Shahid, Khurram Mehboob
    https://doi.org/10.4081/itjm.2025.1870
    983
    PDF: 360
    HTML: 0

  • Right ventricular failure due to subacute massive pulmonary embolism

    Claudio Giumelli, Giacomo Bussolati, Patricia Granauro, Paolo Montanari
    https://doi.org/10.4081/itjm.2025.1747
    1247
    PDF: 93
    VIDEO 1: 40
    HTML: 1

  • Maternal, fetal, and perinatal outcomes of COVID-19-infected pregnancies in Saudi Arabia: a meta-analysis and systematic review

    Ahmad Alwazzan
    https://doi.org/10.4081/itjm.2025.1877
    717
    PDF: 330
    HTML: 0

  • Exploring the determinants of exclusive breastfeeding among postpartum women in northeastern Morocco: fathers’ knowledge as a moderating factor

    Khalid Faraj, Abdellatif Bour
    https://doi.org/10.4081/itjm.2025.1861
    441
    PDF: 342
    HTML: 1

  • Early and late outcomes of emergency coronary bypass grafting in non-ST-segment elevation acute myocardial infarction

    Nguyen Thai Minh, Nguyen Sinh Hien, Bui The Dung, Doan Quoc Hung
    https://doi.org/10.4081/itjm.2025.1808
    637
    PDF: 348
    HTML: 139

  • Role of platelet indices and vitamin D in forecasting deterioration of glycemic control and vascular complications in type 2 diabetes

    Maryam Ahmed Obaid Al Ali, Khalid Abdelsamea Mohamedahmed, Asaad Ma Babker
    https://doi.org/10.4081/itjm.2025.1875
    633
    PDF: 196
    HTML: 25

  • C-reactive protein as a diagnostic marker for ovarian carcinoma

    Angga Dewi Umar Wahyu, Syahrul Rauf, Susiawaty Susiawaty, Maisuri T. Chalid, Nugraha Utama Pelupessy, Irma Savitri
    https://doi.org/10.4081/itjm.2025.1819
    596
    PDF: 192
    HTML: 23

  • Skin lesions and the role of the internist: a series of clinical cases

    Carolina Bologna, Domenico Birra, Marina Lugarà, Antonietta De Sena, Gabriella Oliva, Paolo Tirelli, Pasquale Madonna, Vincenzo Nuzzo
    https://doi.org/10.4081/itjm.2024.1796
    1027
    PDF: 225
    HTML: 1

  • Stochastic Petri net model with random time of Vietnamese ischemic stroke patient treatment process

    Nguyen Tien Dung, Nguyen-Thi Phuong Quynh, Ho Cam Tu, Bui-Thi Thu Huong, Pham-Thi Thuy, Vu-Thi Hoai Thu, Lo Minh Trong, Ho Khanh Lam, Nguyen Phuong Sinh
    https://doi.org/10.4081/itjm.2024.1806
    1020
    PDF: 262
    HTML: 1

  • Obesity: a potential cause of varicocele leading to male infertility

    Zain ul Hasan, Syed Amir Gilani, Asif Hanif, Raham Bacha, Zareen Fatima
    https://doi.org/10.4081/itjm.2024.1827
    982
    PDF: 177
    HTML: 1

  • Profile of dietary supplement consumers in the region of Rabat-Salé-Kénitra, Morocco

    Oumaima Touijri, Btihaj Al Ibrahmi, Yassmine Nahab, Ali Quyou, Moulay Laarbi Ouahidi
    https://doi.org/10.4081/itjm.2024.1857
    745
    PDF: 227
    HTML: 0

  • Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis

    Iranna Kotturshetti, Basavaraj Vastrad, Veena Kori, Chanabasayya Vastrad, Shivakumar Kotrashetti
    https://doi.org/10.4081/itjm.2024.1830
    1315
    PDF: 269
    SUPPLEMENTARY MATERIAL: 162
    HTML: 15

  • Assessment of the knowledge of pregnant women with gestational diabetes regarding diet and physical activity in Morocco

    Hanane Azargui, Btihaj AL Ibrahmi, Abdellatif Bour
    https://doi.org/10.4081/itjm.2024.1849
    888
    PDF: 240
    HTML: 23

  • Is a terminally ill non-cancer patient really forced to stay at the hospital?

    Francesco Serafini, Maria Gabriella Procacci, Elia Vettore, Giulia Cardinali, Fabio Presotto
    https://doi.org/10.4081/itjm.2024.1850
    642
    HTML: 25
    PDF: 250

  • Retrieving the information stored in the donated organ may cause the patient’s personality to change after the transplant operation

    Jamal Al-Karaki, Muhammad Al-Zafar Khan, Phoka Rathebe, Raul Valverde, Alireza Sepehri, Massimo Fioranelli
    https://doi.org/10.4081/itjm.2024.1790
    738
    PDF: 254
    HTML: 19

  • La medicina perioperatoria e il co-management medico-chirurgico: position paper FADOI-ACOI In collaborazione con SISET, SIMIT, SIN, SINPE

    Davide Carrara, Francesco Dentali
    https://doi.org/10.4081/itjm.q.2024.7
    689
    PDF: 682

  • The importance of the cardiology observation unit in the management of patients with cardiovascular diseases: a pilot project

    Manuel Monti, Simone Cappannelli, Marco Cardile, Deborah Cosmi, Tania Di Pasquale, Mariana Cappannelli, Jacopo Fagotti, Pietro Quadalti, Michele Marvardi, Roberto Marchetti, Euro Capponi
    https://doi.org/10.4081/itjm.2024.1840
    755
    PDF: 285
    HTML: 31

  • Safety and efficacy of renal denervation utilizing standard bidirectional EP catheter: preliminary Vietnamese findings

    Tran Ba Hieu, Nguyen Ngoc Quang, Pham Manh Hung
    https://doi.org/10.4081/itjm.2024.1816
    753
    PDF: 325
    HTML: 91

  • Vitamin D and intrauterine growth restriction: a cross-sectional study

    Fadhilah Arnan, Maisuri T. Chalid, Monika Fitria Farid, Efendi Lukas, Ellen Wewengkang
    https://doi.org/10.4081/itjm.2024.1833
    838
    PDF: 327
    HTML: 96

  • Pharmacological interactions in novel oral anticoagulants, statins, and hypertension drugs in patients treated with direct-acting antivirals for hepatitis C: a Delphi Consensus project

    Ivan Gentile, Giancarlo Agnelli, Angelo Avogaro, Claudio Borghi, Alessia Ciancio, Ernesto Claar, Patrizio Pasqualetti, Pasquale Perrone Filardi
    https://doi.org/10.4081/itjm.2024.1846
    876
    PDF: 302
    SUPPLEMENTARY MATERIAL: 213
    ACKNOWLEDGMENTS: 206
    HTML: 100

  • Molecular and hematological spectrum of α-thalassemia in Saudi patients

    Raed Alserihi, Sarah Alswat, Heba Alkhatabi , Haitham M.H. Qutob, Elrashed B. Yasin, Talal Qadah
    https://doi.org/10.4081/itjm.2024.1837
    783
    PDF: 321
    HTML: 99

  • An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

    Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello
    https://doi.org/10.4081/itjm.2024.1836
    823
    PDF: 337
    HTML: 101

  • Association of immunoglobulins and complement levels with pemphigus in patients at the Khartoum Dermatology and Venereal Disease Hospital, Sudan

    Omer Osman Elhag, Mohammed S. Abduhameed, Ismaeel O. Khalid, AbdulAzeem Hijawi, Mohamed O. Andarawi, Saadalnour A. Mustafa, Adil A. Yousif, Shawgi A Elsiddig, Asaad Babker
    https://doi.org/10.4081/itjm.2024.1831
    888
    PDF: 310
    HTML: 102

  • Assessing the effect of implementing a central line care bundle on central line-associated bloodstream infections in a tertiary hospital in Saudi Arabia

    Ohoud Alhumaidan, Zeina Alkudmani, Khaled Alnafee, Sabah Alshuhri, Bandar Alrashid, Jalwa Alkahtany, Afnan Almazrua, Salem Alghamdi
    https://doi.org/10.4081/itjm.2024.1783
    1622
    PDF: 454
    SUPPLEMENTARY MATERIAL: 254
    HTML: 136

  • Sodium-glucose cotransporter 2 inhibition in patients with liver cirrhosis and diabetes: a possible role in ascites control?

    Aurelio Seidita, Francesca Mandreucci, Mirco Pistone, Silvia Calderone, Alessandra Giuliano, Marta Chiavetta, Lydia Giannitrapani, Roberto Citarrella, Maurizio Soresi, Anna Licata, Antonio Carroccio, Stella Compagnoni
    https://doi.org/10.4081/itjm.2024.1829
    1476
    PDF: 412
    SUPPLEMENTARY MATERIAL: 260
    HTML: 106

  • Clinical utility of echocardiography in internal medicine: a narrative review

    Nicola Mumoli, Stefania Marengo
    https://doi.org/10.4081/itjm.2024.1802
    1499
    PDF: 471
    HTML: 123

  • A misleading miscellanea: a COVID-19 patient with fever and cytopenia

    Pietro Bocchi, Lara Zerbini, Elisa Gnappi, Maurizio Ziliotti, Marco Pesci, Luisa Craviotto, Michele Meschi
    https://doi.org/10.4081/itjm.2024.1805
    1396
    PDF: 398
    HTML: 115

  • Ochrobactrum anthropi: a rare case of endocarditis

    Francesca Salvotti, Gilda Rossoni, Maria Chiara Pilia, Pietro Carleo, Veronika Kofler, Cristina Carmignani, Maria Grazia Marin, Fabrizio Paolo Bonfante, Irene Zagni
    https://doi.org/10.4081/itjm.2024.1821
    1238
    PDF: 405
    HTML: 108

  • Incidence and clinicopathological characteristics of breast cancer patients from a single center study

    Alaa Banjar
    https://doi.org/10.4081/itjm.2024.1820
    1266
    PDF: 386
    HTML: 131

  • Patent foramen ovale and stroke: a possible association with deep vein thrombosis

    Raffaele Natale, Luca Maria Capece, Sofia Donnarumma, Pasquale Madonna, Carolina Bologna, Domenico Birra, Antonietta De Sena, Marina Lugarà, Claudio De Luca, Mariavittoria Guerra, Gabriella Oliva, Fabio Granato Corigliano, Paolo Tirelli, Vincenzo Nuzzo
    https://doi.org/10.4081/itjm.2024.1801
    1281
    PDF: 469
    HTML: 148

  • The long-term impact of the COVID-19 pandemic on mental health and quality of life: a retrospective cohort study in northern Vietnam

    Nguyen Thi Hoa, Nguyen Van Tuan, Tran Thi Thu Ha, Nguyen Thanh Long, Nguyen Hoang Yen, Vu Son Tung, Tran Thien Thang, Tran Thi Ha An, Le Cong Thien, Le Thi Thu Ha, Le Thi Hoan
    https://doi.org/10.4081/itjm.2024.1809
    1326
    PDF: 412
    HTML: 123

  • Diagnostic values of adenosine deaminase cytokines in fluid contributed to the detection of extrapulmonary tuberculosis

    Bui-Thi Thu Huong, Nguyen Minh Hien, Nguyen Tien Dung, Le-Thi Minh Hien, Luu Cong Thanh, Luu Vu Dung, Tran Khanh Chi, Nguyen-Van Khiem, Hoang Hai Yen
    https://doi.org/10.4081/itjm.2024.1810
    259
    PDF: 185
    HTML: 2

  • Knowledge, perceptions, and practices of blood donation among undergraduate students at Gulf Medical University, United Arab Emirates: a cross-sectional study

    Asaad M.A. Babker, Kiran S Gopinath, Srija Manimaran, Ibrahim Ali Alsalkhadi, Praveen Kumar Kandakurti, Ahmed Luay Osman
    https://doi.org/10.4081/itjm.2024.1788
    461
    PDF: 190
    SUPPLEMENTARY MATERIAL: 53
    HTML: 123

  • Comparative analysis of advanced polymerase chain reaction-based detection of Parvovirus B19 in first-trimester pregnant women at Thumbay Hospital, Ajman, United Arab Emirates

    Alaa M. Abdalhadi, Asaad Babker, Ahmed Luay Osman, Israa M. Abdalhadi, Mona A. Alblooshi, Fawzia A. AlObeidli, Israa O. Yousif, Hassan Higazi
    https://doi.org/10.4081/itjm.2024.1800
    372
    PDF: 178
    HTML: 6

  • Morphometric and clinical analysis and nutritional and dietary management of malnourished adult patients in the Marrakech Tensift Al Haouz region, Morocco

    Hiba Belmoudden, Btihaj Al Ibrahmi, Abdellatif Bour
    https://doi.org/10.4081/itjm.2024.1804
    254
    PDF: 121
    HTML: 1

  • Prevalence and distribution of dry eye disease among patients with type 2 diabetes in Kosovo

    Drilon Zekaj, Naim Jerliu, Floriana Kukaj-Zekaj, Ali Tonuzi
    https://doi.org/10.4081/itjm.2024.1799
    592
    PDF: 275
    HTML: 3

  • A case of ankylosing spondylitis in female siblings

    Aigerim Abuova, Baglan Abdakhina, Aleksandr Glushan, Zhasken Smagulov, Bibigul Adilbekova, Svetlana Trofimova, Assel Meiramova
    https://doi.org/10.4081/itjm.2024.1797
    491
    PDF: 169
    HTML: 40

  • Segmental arterial mediolysis: a challenging diagnosis in internal medicine

    Giulia Bombardieri, Alessandra Rustici, Michele Caselli, Chiara Chirico, Veronica Bocchi, Andrea Montagnani
    https://doi.org/10.4081/itjm.2024.1795
    399
    PDF: 187
    HTML: 55

  • Impressive weight loss induced by a very low-calorie ketogenic diet in a morbidly complex obese patient with a recent episode of acute kidney injury and advanced chronic kidney disease: a case report

    Vincenzo Trapanese, Maria Chiara Pelle, Maria Capria, Nazareno Carullo, Clara Vatalaro, Francesca Cosentino, Melania Melina, Maria Resilde Natale, Federica Giofrè, Franco Arturi
    https://doi.org/10.4081/itjm.2024.1787
    535
    PDF: 197
    HTML: 109

  • Correlation between diet, body mass index, and lipid profile in Kosovar women treated for primary infertility

    Fatjona Gashi, Muhamet Kadrija, Zafer Gashi, Mila Arapcheska, Shkelzen Elezaj, Fitore Gashi, Fitim Gashi, Gentian Elezaj, Liridon Elezaj
    https://doi.org/10.4081/itjm.2024.1784
    464
    PDF: 222
    HTML: 17

  • The value of computed tomography perfusion for assessing the response of hepatocellular carcinoma to transarterial chemoembolization

    Bui Quang Huynh, Nguyen Duy Hung, Le Thanh Dung, Nguyen-Thi Thu, Nguyen-Thi Hai Anh, Ngo Quang Duy, Nguyen Minh Duc
    https://doi.org/10.4081/itjm.2024.1768
    414
    PDF: 280
    HTML: 37

  • Concern for medical students due to their cell phones’ comparatively high contamination with Pantoea agglomerans bacteria with reduced sensitivity to some antimicrobials

    Ahmed E. Taha
    https://doi.org/10.4081/itjm.2024.1767
    473
    PDF: 226
    HTML: 33
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