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The Italian Journal of Medicine (ITJM) is the official journal of FADOI, the Federation of Associations of Hospital Doctors on Internal Medicine and focus to describe the complex and variable situations confronted by Internists in daily practice. ITJM aims to promote excellence in the practice of internal medicine in hospitals and to disseminate the results of clinical research in internal medicine departments. The journal also contributes to the updating of hospital internists on general topics concerning public health, including ethical, legal, economical and health policy issues. ITJM is a quarterly peer-reviewed journal aiming to publish highest-quality material covering original basic and clinical research on all aspects of internal medicine. The Journal includes original clinical research papers, reviews, case reports and specific sections dedicated to clinical pharmacology, chronic diseases, health management. ITJM is currently indexed in Web of Science/ESCI, Scopus and DOAJ since September 2009.

New Articles

  • Gender differences and post-pandemic mental health impacts: a mediation study on Vietnamese adolescents

    Thanh Long Nguyen, Victor Storm, Lam Toi Phung, Cong Thien Le, Thi Thu Ha Le, Thi Hoa Nguyen, Son Tung Vu, Thien Thang Tran, Minh Hanh Vu, Van Tuan Nguyen
    https://doi.org/10.4081/itjm.2025.1888
    0
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    SUPPLEMENTARY MATERIAL: 0

  • Mentzer Index and Red Cell Distribution Width Index in differentiating iron deficiency anemia and β-thalassemia trait

    Rabab H. Elshaikh, Ashok Kumar Sah, Abdelrahman Mohamed Abukanna, Abdulrahman Algarni, Ammar Abdelmola, Hussam Ali Osma, Tagwa Yousif Elsayed Yousif, Elryah I. Ali, Hiba Ali, Ayman Hussein Alfeel
    https://doi.org/10.4081/itjm.2025.1892
    38
    PDF: 9

  • Peritoneal involvement in acute pericarditis with polyserositis may mimic acute cholecystitis: a case report

    Emanuele Bizzi, Francesco Moda, Massimo Pancrazi, Alice Pedroli, Ruggiero Mascolo, Antonio Luca Brucato
    https://doi.org/10.4081/itjm.2025.1931
    35
    PDF: 14

  • The man from the stars: a narrative approach to neglected diseases

    Paolo Agostinis, Teresa Michelutti, Laura Iogna Prat, Omar Simonetti
    https://doi.org/10.4081/itjm.2025.1900
    67
    PDF: 27

  • The role of genetic variations in metabolic syndrome: insights into etiology, diagnosis, and management

    Darla Srinivasa Rao, Ajay Kumar, Shagun Agarwal, Rabab Hassan Elshaikh, AjabSingh Choudhary, Ranjay Kumar Choudhary, Assad M A Babker, Rohit Rathore, Zhannat Nurmakhanova, Zhanar Nurgaliyeva, Abdugani Musayev, Ashok Kumar Sah
    https://doi.org/10.4081/itjm.2025.1908
    180
    PDF: 77

  • Embracing artificial intelligence in internal medicine: a tool for physicians and patients

    Matteo Giorgi-Pierfranceschi
    https://doi.org/10.4081/itjm.2025.1791
    98
    PDF: 27

  • Diagnostic and therapeutic care pathway of the Cardiac Network for Heart Failure

    Pasquale Palmiero, Matteo Durante, Maria Maiello, Valentina D’Andria, Cosima Caputo, Lucia Giordano
    https://doi.org/10.4081/itjm.2025.1927
    157
    PDF: 54
    HTML: 1

  • A toothpick man user with COVID-19

    Francesco Serafini, Elia Vettore, Fabio Presotto
    https://doi.org/10.4081/itjm.2025.1897
    103
    PDF: 44
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  • CO-St (COVID 19-study): sex differences in the treatment of COVID-19

    Manuel Monti, Tiziana Ciarambino, Filomena Pietrantonio, Sara Rotunno, Alessandra Fiorentini, Rosalba Cipriani, Giuseppe Campagna, Giuseppe Straface, Eleonora Pistella, Mauro Giordano, Orazio Valerio Giannico, Roberto Marchetti, Federica Lorenzi, Francesco Rosiello
    https://doi.org/10.4081/itjm.2025.1916
    177
    PDF: 63
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  • Visceral leishmaniasis and lymphoma: a rare and dangerous couple

    Nicola Battino, Antonio Pisano
    https://doi.org/10.4081/itjm.2025.1843
    161
    PDF: 61
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  • Evaluation of the renal function among sickle cell patients: a cross-sectional study

    Talal Qadah, Anwar Refaei
    https://doi.org/10.4081/itjm.2025.1868
    114
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    SUPPLEMENTARY MATERIAL: 16
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  • Virus-induced asthma exacerbations in Vietnamese preschoolers

    Nguyen Thuy Van Thao, Tran Anh Tuan, Pham Hung Van, Le Thuong Vu
    https://doi.org/10.4081/itjm.2025.1818
    106
    PDF: 48
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  • Acute kidney failure due to varicella-zoster virus solved by early antiviral treatment based on brivudin

    Fulvia Paolozzi, Pierpaolo Di Micco, Antonella Giliberti, Gianluca Latte, Maria Teresa Feola, Immacolata Gaia Paduano, Concetta Schiano, Maurizio Latte
    https://doi.org/10.4081/itjm.2025.1786
    169
    PDF: 109
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  • Serum transferrin level in type-2 diabetic patients in association with sociodemographic profile and dietary habits

    Anza Khan, Uzma Rafi, Riffat Mehboob, Sajid Hameed, Uzma Malik, Zainab Zubair, Imran Shahid
    https://doi.org/10.4081/itjm.2025.1873
    169
    PDF: 112
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  • An algorithm for the management of chronic obstructive pulmonary disease patients in units of internal medicine

    Ombretta Para, Carmen Stabile, Donato Cinquepalmi, Maria Sandra Magnoni, Francesco Nasso, Flavio Tangianu, Mauro Silingardi, Antonella Valerio, Dario Manfellotto, Francesco Dentali
    https://doi.org/10.4081/itjm.2025.1838
    396
    PDF: 747
    HTML: 1

  • The incidence of bleeding in patients with nonvalvular atrial fibrillation using anticoagulants: a real-world report with the biggest Vietnamese data

    Bui The Dung, Cao Ngoc Mai Han, Tran Hoa, Nguyen Thanh Hien
    https://doi.org/10.4081/itjm.2025.1807
    1569
    PDF: 70
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  • The unseen connection: laryngeal carcinoma and thrombosis of the internal jugular vein

    Laura Leci-Tahiri, Lisa Tahiri, Valbona Zhjeqi, Emina Ramku
    https://doi.org/10.4081/itjm.2025.1882
    1600
    PDF: 63
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  • Predictive value of Frank’s sign for obstructive coronary artery disease confirmed by coronary computed tomography angiography

    Truong Phi Hung, Nguyen Minh Kha, Dang Tuong Vi, Tran Trong Nhan, Hoang Van Sy
    https://doi.org/10.4081/itjm.2025.1863
    1554
    PDF: 148
    SUPPLEMENTARY MATERIAL: 31
    HTML: 3

  • Right ventricular failure due to subacute massive pulmonary embolism

    Claudio Giumelli, Giacomo Bussolati, Patricia Granauro, Paolo Montanari
    https://doi.org/10.4081/itjm.2025.1747
    1297
    PDF: 116
    VIDEO 1: 73
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  • First evidence of immunomodulation of the renin-angiotensin system through substance P/neurokinin 1 receptor: a case and control study in hypertension and cardiac patients

    Ibrahim M. Alanazi, Riffat Mehboob, Ayesha Tariq, Sajid Hameed, Uzma Malik, Noreen Sarwar, Imran Shahid, Khurram Mehboob
    https://doi.org/10.4081/itjm.2025.1870
    1023
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  • Maternal, fetal, and perinatal outcomes of COVID-19-infected pregnancies in Saudi Arabia: a meta-analysis and systematic review

    Ahmad Alwazzan
    https://doi.org/10.4081/itjm.2025.1877
    754
    PDF: 353
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  • Exploring the determinants of exclusive breastfeeding among postpartum women in northeastern Morocco: fathers’ knowledge as a moderating factor

    Khalid Faraj, Abdellatif Bour
    https://doi.org/10.4081/itjm.2025.1861
    481
    PDF: 377
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  • Early and late outcomes of emergency coronary bypass grafting in non-ST-segment elevation acute myocardial infarction

    Nguyen Thai Minh, Nguyen Sinh Hien, Bui The Dung, Doan Quoc Hung
    https://doi.org/10.4081/itjm.2025.1808
    680
    PDF: 372
    HTML: 140

  • C-reactive protein as a diagnostic marker for ovarian carcinoma

    Angga Dewi Umar Wahyu, Syahrul Rauf, Susiawaty Susiawaty, Maisuri T. Chalid, Nugraha Utama Pelupessy, Irma Savitri
    https://doi.org/10.4081/itjm.2025.1819
    697
    PDF: 220
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  • Role of platelet indices and vitamin D in forecasting deterioration of glycemic control and vascular complications in type 2 diabetes

    Maryam Ahmed Obaid Al Ali, Khalid Abdelsamea Mohamedahmed, Asaad Ma Babker
    https://doi.org/10.4081/itjm.2025.1875
    741
    PDF: 232
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  • Skin lesions and the role of the internist: a series of clinical cases

    Carolina Bologna, Domenico Birra, Marina Lugarà, Antonietta De Sena, Gabriella Oliva, Paolo Tirelli, Pasquale Madonna, Vincenzo Nuzzo
    https://doi.org/10.4081/itjm.2024.1796
    1063
    PDF: 240
    HTML: 1

  • Stochastic Petri net model with random time of Vietnamese ischemic stroke patient treatment process

    Nguyen Tien Dung, Nguyen-Thi Phuong Quynh, Ho Cam Tu, Bui-Thi Thu Huong, Pham-Thi Thuy, Vu-Thi Hoai Thu, Lo Minh Trong, Ho Khanh Lam, Nguyen Phuong Sinh
    https://doi.org/10.4081/itjm.2024.1806
    1064
    PDF: 280
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  • Obesity: a potential cause of varicocele leading to male infertility

    Zain ul Hasan, Syed Amir Gilani, Asif Hanif, Raham Bacha, Zareen Fatima
    https://doi.org/10.4081/itjm.2024.1827
    1046
    PDF: 194
    HTML: 1

  • Profile of dietary supplement consumers in the region of Rabat-Salé-Kénitra, Morocco

    Oumaima Touijri, Btihaj Al Ibrahmi, Yassmine Nahab, Ali Quyou, Moulay Laarbi Ouahidi
    https://doi.org/10.4081/itjm.2024.1857
    780
    PDF: 238
    HTML: 0

  • Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis

    Iranna Kotturshetti, Basavaraj Vastrad, Veena Kori, Chanabasayya Vastrad, Shivakumar Kotrashetti
    https://doi.org/10.4081/itjm.2024.1830
    1420
    PDF: 293
    SUPPLEMENTARY MATERIAL: 163
    HTML: 15

  • Assessment of the knowledge of pregnant women with gestational diabetes regarding diet and physical activity in Morocco

    Hanane Azargui, Btihaj AL Ibrahmi, Abdellatif Bour
    https://doi.org/10.4081/itjm.2024.1849
    931
    PDF: 262
    HTML: 23

  • Retrieving the information stored in the donated organ may cause the patient’s personality to change after the transplant operation

    Jamal Al-Karaki, Muhammad Al-Zafar Khan, Phoka Rathebe, Raul Valverde, Alireza Sepehri, Massimo Fioranelli
    https://doi.org/10.4081/itjm.2024.1790
    782
    PDF: 276
    HTML: 25

  • Is a terminally ill non-cancer patient really forced to stay at the hospital?

    Francesco Serafini, Maria Gabriella Procacci, Elia Vettore, Giulia Cardinali, Fabio Presotto
    https://doi.org/10.4081/itjm.2024.1850
    671
    HTML: 27
    PDF: 259

  • La medicina perioperatoria e il co-management medico-chirurgico: position paper FADOI-ACOI In collaborazione con SISET, SIMIT, SIN, SINPE

    Davide Carrara, Francesco Dentali
    https://doi.org/10.4081/itjm.q.2024.7
    719
    PDF: 717

  • The importance of the cardiology observation unit in the management of patients with cardiovascular diseases: a pilot project

    Manuel Monti, Simone Cappannelli, Marco Cardile, Deborah Cosmi, Tania Di Pasquale, Mariana Cappannelli, Jacopo Fagotti, Pietro Quadalti, Michele Marvardi, Roberto Marchetti, Euro Capponi
    https://doi.org/10.4081/itjm.2024.1840
    786
    PDF: 303
    HTML: 34

  • Safety and efficacy of renal denervation utilizing standard bidirectional EP catheter: preliminary Vietnamese findings

    Tran Ba Hieu, Nguyen Ngoc Quang, Pham Manh Hung
    https://doi.org/10.4081/itjm.2024.1816
    791
    PDF: 353
    HTML: 92

  • Vitamin D and intrauterine growth restriction: a cross-sectional study

    Fadhilah Arnan, Maisuri T. Chalid, Monika Fitria Farid, Efendi Lukas, Ellen Wewengkang
    https://doi.org/10.4081/itjm.2024.1833
    888
    PDF: 347
    HTML: 101

  • Pharmacological interactions in novel oral anticoagulants, statins, and hypertension drugs in patients treated with direct-acting antivirals for hepatitis C: a Delphi Consensus project

    Ivan Gentile, Giancarlo Agnelli, Angelo Avogaro, Claudio Borghi, Alessia Ciancio, Ernesto Claar, Patrizio Pasqualetti, Pasquale Perrone Filardi
    https://doi.org/10.4081/itjm.2024.1846
    908
    PDF: 317
    SUPPLEMENTARY MATERIAL: 215
    ACKNOWLEDGMENTS: 206
    HTML: 101

  • Molecular and hematological spectrum of α-thalassemia in Saudi patients

    Raed Alserihi, Sarah Alswat, Heba Alkhatabi , Haitham M.H. Qutob, Elrashed B. Yasin, Talal Qadah
    https://doi.org/10.4081/itjm.2024.1837
    823
    PDF: 336
    HTML: 100

  • An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

    Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello
    https://doi.org/10.4081/itjm.2024.1836
    849
    PDF: 350
    HTML: 101

  • Association of immunoglobulins and complement levels with pemphigus in patients at the Khartoum Dermatology and Venereal Disease Hospital, Sudan

    Omer Osman Elhag, Mohammed S. Abduhameed, Ismaeel O. Khalid, AbdulAzeem Hijawi, Mohamed O. Andarawi, Saadalnour A. Mustafa, Adil A. Yousif, Shawgi A Elsiddig, Asaad Babker
    https://doi.org/10.4081/itjm.2024.1831
    921
    PDF: 325
    HTML: 102

  • Sodium-glucose cotransporter 2 inhibition in patients with liver cirrhosis and diabetes: a possible role in ascites control?

    Aurelio Seidita, Francesca Mandreucci, Mirco Pistone, Silvia Calderone, Alessandra Giuliano, Marta Chiavetta, Lydia Giannitrapani, Roberto Citarrella, Maurizio Soresi, Anna Licata, Antonio Carroccio, Stella Compagnoni
    https://doi.org/10.4081/itjm.2024.1829
    1509
    PDF: 433
    SUPPLEMENTARY MATERIAL: 260
    HTML: 107

  • Assessing the effect of implementing a central line care bundle on central line-associated bloodstream infections in a tertiary hospital in Saudi Arabia

    Ohoud Alhumaidan, Zeina Alkudmani, Khaled Alnafee, Sabah Alshuhri, Bandar Alrashid, Jalwa Alkahtany, Afnan Almazrua, Salem Alghamdi
    https://doi.org/10.4081/itjm.2024.1783
    1726
    PDF: 487
    SUPPLEMENTARY MATERIAL: 255
    HTML: 149

  • Clinical utility of echocardiography in internal medicine: a narrative review

    Nicola Mumoli, Stefania Marengo
    https://doi.org/10.4081/itjm.2024.1802
    1557
    PDF: 498
    HTML: 126

  • A misleading miscellanea: a COVID-19 patient with fever and cytopenia

    Pietro Bocchi, Lara Zerbini, Elisa Gnappi, Maurizio Ziliotti, Marco Pesci, Luisa Craviotto, Michele Meschi
    https://doi.org/10.4081/itjm.2024.1805
    1423
    PDF: 410
    HTML: 115

  • Ochrobactrum anthropi: a rare case of endocarditis

    Francesca Salvotti, Gilda Rossoni, Maria Chiara Pilia, Pietro Carleo, Veronika Kofler, Cristina Carmignani, Maria Grazia Marin, Fabrizio Paolo Bonfante, Irene Zagni
    https://doi.org/10.4081/itjm.2024.1821
    1270
    PDF: 417
    HTML: 108

  • Patent foramen ovale and stroke: a possible association with deep vein thrombosis

    Raffaele Natale, Luca Maria Capece, Sofia Donnarumma, Pasquale Madonna, Carolina Bologna, Domenico Birra, Antonietta De Sena, Marina Lugarà, Claudio De Luca, Mariavittoria Guerra, Gabriella Oliva, Fabio Granato Corigliano, Paolo Tirelli, Vincenzo Nuzzo
    https://doi.org/10.4081/itjm.2024.1801
    1308
    PDF: 483
    HTML: 151

  • The long-term impact of the COVID-19 pandemic on mental health and quality of life: a retrospective cohort study in northern Vietnam

    Nguyen Thi Hoa, Nguyen Van Tuan, Tran Thi Thu Ha, Nguyen Thanh Long, Nguyen Hoang Yen, Vu Son Tung, Tran Thien Thang, Tran Thi Ha An, Le Cong Thien, Le Thi Thu Ha, Le Thi Hoan
    https://doi.org/10.4081/itjm.2024.1809
    1368
    PDF: 426
    HTML: 125

  • Incidence and clinicopathological characteristics of breast cancer patients from a single center study

    Alaa Banjar
    https://doi.org/10.4081/itjm.2024.1820
    1301
    PDF: 401
    HTML: 131

  • Diagnostic values of adenosine deaminase cytokines in fluid contributed to the detection of extrapulmonary tuberculosis

    Bui-Thi Thu Huong, Nguyen Minh Hien, Nguyen Tien Dung, Le-Thi Minh Hien, Luu Cong Thanh, Luu Vu Dung, Tran Khanh Chi, Nguyen-Van Khiem, Hoang Hai Yen
    https://doi.org/10.4081/itjm.2024.1810
    298
    PDF: 205
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