Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management

Submitted: 3 October 2014
Accepted: 7 February 2015
Published: 15 December 2015
Abstract Views: 4408
PDF: 1159
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Primary hyperparathyroidism (PHPT) is a clinical condition characterized by overactive parathyroid gland secretion of parathyroid hormone with concurrent alteration of the phosphocalcemic metabolism. We present a literature review on primary hyperparathyroidism addressing key on clinical presentation, causes, medical and surgical treatment at the best of our knowledge. Based on this review we confirm the role of serum calcium and serum level examination, as well as we define the definitive treatment for PHPT being parathyroidectomy. In case of contraindication for surgery, medical treatment can play a relevant role.

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Percivale, A., Gnerre, P., Damonte, G., Buscaglia, S., Monachesi, M., Parodi, L., Tassara, R., Curletti, G., & Saccomani, G. (2015). Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management. Italian Journal of Medicine, 9(4), 330–345. https://doi.org/10.4081/itjm.2015.547