https://doi.org/10.4081/itjm.2024.1767

Concern for medical students due to their cell phones’ comparatively high contamination with Pantoea agglomerans bacteria with reduced sensitivity to some antimicrobials

Vol. 18 No. 3 (2024)
Submitted: 2 July 2024
Accepted: 24 July 2024
Published: 13 September 2024
Healthcare, antimicrobial resistance, infectious diseases, antimicrobial surfaces
Abstract Views: 212
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Authors

Ahmed E. Taha
aeattia@ju.edu.sa
https://orcid.org/0000-0002-5766-4495
Microbiology and Immunology Unit, Department of Pathology, College of Medicine, Jouf University, Sakaka, Saudi Arabia.

The significance of Pantoea agglomerans bacteria in diseases linked to healthcare is underappreciated due to a shortage of information on their spread. This is the first study in Saudi Arabia to examine the possible contribution of medical students’ cell phones (CPs) to the transmission of P. agglomerans to hospitalized patients and to evaluate their antibiotic susceptibility profiles. In total, 250 CPs were swabbed. P. agglomerans was isolated and identified using standard techniques. The suspected colonies were confirmed by the Vitek 2 compact system. The isolates’ antimicrobial susceptibility profiles were assessed using Epsilon assays, and the results were interpreted according to Clinical and Laboratory Standards Institute guidelines. The frequency of P. agglomerans contamination of CPs was found to be relatively high (20.40%; 51 isolates/250 samples). Many isolates showed varying degrees of reduced sensitivity to ampicillin, aztreonam, cefazolin, cefotaxime, cefuroxime, and ertapenem antibiotics. To implement optimal infection prevention and control policies regarding the possibility of antibiotic-resistant P. agglomerans transmission through medical students’ contact points with hospitalized patients during their frequent activities in healthcare settings, health policymakers may find value in utilizing this study’s results.

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Citations

Crossref
Scopus
Google Scholar
Europe PMC
Hosseini Fard R, Hosseini Fard R, Moradi M, Hashemipour MA. Evaluation of the cell phone microbial contamination in dental and engineering schools: effect of antibacterial spray. J Epidemiol Glob Health 2018;8:143-8. DOI: https://doi.org/10.2991/j.jegh.2017.10.004
Adjei ND. The use and effect of smart phones in students ‘learning activities: evidence from the University of Ghana, Legon. 2019. Available from: https://digitalcommons.unl.edu/libphilprac/2851. Accessed on: 11/03/2024.
Bodena D, Teklemariam Z, Balakrishnan S, Tesfa T. Bacterial contamination of mobile phones of health professionals in Eastern Ethiopia: antimicrobial susceptibility and associated factors. Trop Med Health 2019;47:15. DOI: https://doi.org/10.1186/s41182-019-0144-y
Sadeeq T, Arikan A, Sanlidag T, et al. Big concern for public health: microbial contamination of mobile phones. J Infect Dev Ctries 2021;15:798-804. DOI: https://doi.org/10.3855/jidc.13708
Mazzeffi M, Galvagno S, Rock C. Prevention of healthcare-associated infections in intensive care unit patients. Anesthesiology 2021;135:1122-31. DOI: https://doi.org/10.1097/ALN.0000000000004017
Tambong JT. Taxogenomics and systematics of the genus Pantoea. Front Microbiol 2019;10:2463. DOI: https://doi.org/10.3389/fmicb.2019.02463
Cheng A, Liu CY, Tsai HY, et al. Bacteremia caused by Pantoea agglomerans at a medical center in Taiwan, 2000-2010. J Microbiol Immunol Infect 2013;46:187-94. DOI: https://doi.org/10.1016/j.jmii.2012.05.005
Walterson AM, Stavrinides J. Pantoea: insights into a highly versatile and diverse genus within the Enterobacteriaceae. FEMS Microbiol Rev 2015;39:968-84. DOI: https://doi.org/10.1093/femsre/fuv027
Mardaneh J, Dallal MM. Isolation, identification and antimicrobial susceptibility of Pantoea (Enterobacter) agglomerans isolated from consumed powdered infant formula milk (PIF) in NICU ward: first report from Iran. Iran J Microbiol 2013;5:263-7.
Matsaniotis NS, Syriopoulou VP, Theodoridou MC, et al. Enterobacter sepsis in infants and children due to contaminated intravenous fluids. Infect Control 1984;5:471-7. DOI: https://doi.org/10.1017/S0195941700060872
Flores Popoca EO, Miranda García M, Romero Figueroa S, et al. Pantoea agglomerans in immunodeficient patients with different respiratory symptoms. ScientificWorldJournal 2012;2012:156827. DOI: https://doi.org/10.1100/2012/156827
Cruz AT, Cazacu AC, Allen CH. Pantoea agglomerans, a plant pathogen causing human disease. J Clin Microbiol 2007;45:1989-92. DOI: https://doi.org/10.1128/JCM.00632-07
Dutkiewicz J, Mackiewicz B, Kinga Lemieszek M, et al. Pantoea agglomerans: a mysterious bacterium of evil and good. Part III. Deleterious effects: infections of humans, animals and plants. Ann Agric Environ Med 2016;23:197-205. DOI: https://doi.org/10.5604/12321966.1203878
Maki DG, Rhame FS, Mackel DC, Bennett JV. Nationwide epidemic of septicemia caused by contaminated intravenous products. I. Epidemiologic and clinical features. Am J Med 1976;60:471-85. DOI: https://doi.org/10.1016/0002-9343(76)90713-0
Habsah H, Zeehaida M, Van Rostenberghe H, et al. An outbreak of Pantoea spp. in a neonatal intensive care unit secondary to contaminated parenteral nutrition. J Hosp Infect 2005;61:213-8. DOI: https://doi.org/10.1016/j.jhin.2005.01.004
Liberto MC, Matera G, Puccio R, et al. Six cases of sepsis caused by Pantoea agglomerans in a teaching hospital. New Microbiol 2009;32:119-23.
Francis MJ, Chin J, Lomiguen CM, Glaser A. Cotton fever resulting in Enterobacter asburiae endocarditis. IDCases 2019;19:e00688. DOI: https://doi.org/10.1016/j.idcr.2019.e00688
Penner M, Romans B, Tah L, et al. Successful treatment of Pantoea agglomerans bacteremia using oral antibiotics. Case Rep Infect Dis 2022;2022:6136265. DOI: https://doi.org/10.1155/2022/6136265
Mustapha SS, Ibrahim M, Aliyu S, Abdulkadir I. Enterobacter agglomerans, an uncommon cause of community-acquired bacterial infection in neonates. J Trop Pediatr 2022;68:fmac085. DOI: https://doi.org/10.1093/tropej/fmac085
Mushabati NA, Samutela MT, Yamba K, et al. Bacterial contamination of mobile phones of healthcare workers at the University Teaching Hospital, Lusaka, Zambia. Infect Prev Pract 2021;3:100126. DOI: https://doi.org/10.1016/j.infpip.2021.100126
Bilal JA, Ahmad MI, Robaee AA, et al. Pattern of bacterial colonization of atopic dermatitis in Saudi children. J Clin Diagn Res 2013;7:1968-70. DOI: https://doi.org/10.7860/JCDR/2013/5506.3371
Zakai S, Mashat A, Abumohssin A, et al. Bacterial contamination of cell phones of medical students at King Abdulaziz University, Jeddah, Saudi Arabia. J Microsc Ultrastruct 2016;4:143-6. DOI: https://doi.org/10.1016/j.jmau.2015.12.004
Shami A, Al-Mijalli S, Pongchaikul P, et al. The prevalence of the culturable human skin aerobic bacteria in Riyadh, Saudi Arabia. BMC Microbiol 2019;19:189. DOI: https://doi.org/10.1186/s12866-019-1569-5
Al-Beeshi NZ, Alohali RM, Torchyan AA, Somily AM. The bacterial colonization of healthcare workers’ mobile phones in a large tertiary care teaching hospital in Saudi Arabia. J Infect Dev Ctries 2021;15:1314-20. DOI: https://doi.org/10.3855/jidc.13201
Maurer FP, Christner M, Hentschke M, Rohde H. Advances in rapid identification and susceptibility testing of bacteria in the clinical microbiology laboratory: implications for patient care and antimicrobial stewardship programs. Infect Dis Rep 2017;9:6839. DOI: https://doi.org/10.4081/idr.2017.6839
CLSI. Performance standards for antimicrobial susceptibility testing. 31st ed. CLSI supplement M100. Clinical and Laboratory Standards Institute; 2021.
Raza I, Raza A, Razaa SA, et al. Surface microbiology of smartphone screen protectors among healthcare professionals. Cureus 2017;9:e1989. DOI: https://doi.org/10.7759/cureus.1989
Taher NM. Pathogenic bacteria isolated from personal cell phones of health care staff in Iraqi hospitals. J Pure Appl Microbiol 2019;13:1145-50. DOI: https://doi.org/10.22207/JPAM.13.2.53
Galazzi A, Panigada M, Broggi E, et al. Microbiological colonization of healthcare workers’ mobile phones in a tertiary-level Italian intensive care unit. Intensive Crit Care Nurs 2019;52:17-21. DOI: https://doi.org/10.1016/j.iccn.2019.01.005
Abd-ulnabi RM, Alshaheen ZG, Abdul-jabbar RA. Microbial incidence and antibiotic susceptibility for bacterial isolates in the mobile phone of healthcare workers and university employments in Basrah city. J Pure Appl Microbiol 2020;14:1863-70. DOI: https://doi.org/10.22207/JPAM.14.3.25
Qureshi NQ, Mufarrih SH, Irfan S, et al. Mobile phones in the orthopedic operating room: Microbial colonization and antimicrobial resistance. World J Orthop 2020;11:252-64. DOI: https://doi.org/10.5312/wjo.v11.i5.252
Asfaw T, Genetu D. High rate of bacterial contamination on healthcare worker’s mobile phone and potential role in dissemination of healthcare-associated infection at Debre Berhan referral hospital, north Shoa zone, Ethiopia. Risk Manag Healthc Policy 2021;14:2601-8. DOI: https://doi.org/10.2147/RMHP.S313387
Olu-Taiwo M, Laryea CA, Kweku Mykels D, Forson AO. Multidrug-resistant bacteria on the mobile phones and computer keyboards of healthcare university students in Ghana. Can J Infect Dis Med Microbiol 2021;2021:6647959. DOI: https://doi.org/10.1155/2021/6647959
Banawas S, Abdel-Hadi A, Alaidarous M, et al. Multidrug-resistant bacteria associated with cell phones of healthcare professionals in selected hospitals in Saudi Arabia. Can J Infect Dis Med Microbiol 2018;2018:6598918. DOI: https://doi.org/10.1155/2018/6598918
AlOmani MA, Anwer R, Sandoqa AM, et al. Elucidation of practices of mobile phone hygiene and identification of the microorganisms: a perspective study from Riyadh, Saudi Arabia. J Pure Appl Microbiol 2020;14:1761-8. DOI: https://doi.org/10.22207/JPAM.14.3.14
Sadat-Ali M, Al-Omran AK, Azam Q, et al. Bacterial flora on cell phones of health care providers in a teaching institution. Am J Infect Control 2010;38:404-5. DOI: https://doi.org/10.1016/j.ajic.2009.08.007
Shahaby AF, Awad NS, El-Tarras AE, Bahobial AS. Mobile phone as potential reservoirs of bacterial pathogens. African J Biotechnol 2012;11:15896-904. DOI: https://doi.org/10.5897/AJB12.1836
Dhayhi N, Kameli N, Salawi M, et al. Bacterial contamination of mobile phones used by healthcare workers in critical care units: a cross-sectional study from Saudi Arabia. Microorganisms 2023;11:1986. DOI: https://doi.org/10.3390/microorganisms11081986
Bicudo EL, Macedo VO, Carrara MA, et al. Nosocomial outbreak of Pantoea agglomerans in a pediatric urgent care center. Braz J Infect Dis 2007;11:281-4. DOI: https://doi.org/10.1590/S1413-86702007000200023
Boszczowski I, Nóbrega de Almeida Júnior J, Peixoto de Miranda EJ, et al. Nosocomial outbreak of Pantoea agglomerans bacteraemia associated with contaminated anticoagulant citrate dextrose solution: new name, old bug? J Hosp Infect 2012;80:255-8. DOI: https://doi.org/10.1016/j.jhin.2011.12.006
Hrabińska-Zachwieja J, Krukowski J, Tubek S, Zeljaś A. Bacterial endocarditis caused by Enterobacter agglomerans in a patient with mitral valve prolapse. Wiad Lek 1989;42:453-5.
Rasmussen SW, Koczulab B. Transfusion associated bacteremia and septic shock due to Erwinia herbicola. Scand J Infect Dis 1992;24:241-3. DOI: https://doi.org/10.3109/00365549209052619
Shubov A, Jagannathan P, Chin-Hong PV. Pantoea agglomerans pneumonia in a heart-lung transplant recipient: case report and a review of an emerging pathogen in immunocompromised hosts. Transpl Infect Dis 2011;13:536-9. DOI: https://doi.org/10.1111/j.1399-3062.2011.00630.x
Kurşun O, Unal N, Cesur S, et al. A case of ventilator-associated pneumonia due to Pantoea agglomerans. Mikrobiyol Bul 2012;46:295-8. [Article in Turkish].
Izzo I, Lania D, Castro A, et al. Seven cases of port-a-cath contamination caused by Pantoea agglomerans in the oncological service of Iseo hospital, Brescia (Italy). Infez Med 2014;22:152-5.
Kazancioglu R, Buyukaydin B, Iraz M, et al. An unusual cause of peritonitis in peritoneal dialysis patients: Pantoea agglomerans. J Infect Dev Ctries 2014;8:919-22. DOI: https://doi.org/10.3855/jidc.3785
Al-Damluji S, Dickinson CM, Beck A. Enterobacter agglomerans: a new cause of primary pneumonia. Thorax 1982;37:865-6. DOI: https://doi.org/10.1136/thx.37.11.865
García-Pardo G, Martí N, Vidal F, Richart C. Enterobacter agglomerans pneumonia outside of the hospital in a previously health patient. Enferm Infecc Microbiol Clin 1999;17:48. [Article in Spanish].
Naha K, Ramamoorthi, Prabhu M. Spontaneous septicaemia with multi-organ dysfunction--a new face for Pantoe agglomerans? Asian Pac J Trop Med 2012;5:83-4. DOI: https://doi.org/10.1016/S1995-7645(11)60252-6
Cicchetti R, Iacobini M, Midulla F, et al. Pantoea agglomerans sepsis after rotavirus gastroenteritis. Pediatr Infect Dis J 2006;25:280-1. DOI: https://doi.org/10.1097/01.inf.0000202211.64017.c6
Siwakoti S, Sah R, Rajbhandari RS, Khanal B. Pantoea agglomerans infections in children: report of two cases. Case Rep Pediatr 2018;2018:4158734. DOI: https://doi.org/10.1155/2018/4158734
Haralampidou H, Ladomenou F, Gkountoula T, et al. Pantoea agglomerans bacteremia: a rare case of bacteremia in an immunocompetent four-year-old child. Cureus 2022;14:e26080. DOI: https://doi.org/10.7759/cureus.26080
Ulger F, Dilek A, Esen S, et al. Are healthcare workers’ mobile phones a potential source of nosocomial infections? Review of the literature. J Infect Dev Ctries 2015;9:1046-53. DOI: https://doi.org/10.3855/jidc.6104
Wilson J. Infection Control in Clinical Practice. Edinburgh, Scotland: Bailliere Tindall. 2006.
De Groote P, Blot K, Conoscenti E, et al. Mobile phones as a vector for healthcare-associated infection: a systematic review. Intensive Crit Care Nurs 2022;72:103266. DOI: https://doi.org/10.1016/j.iccn.2022.103266
Murugaiyan J, Kumar PA, Rao GS, et al. Progress in alternative strategies to combat antimicrobial resistance: focus on antibiotics. Antibiotics 2022;11:200. DOI: https://doi.org/10.3390/antibiotics11020200
Elbehiry A, Marzouk E, Abalkhail A, et al. The development of technology to prevent, diagnose, and manage antimicrobial resistance in healthcare-associated infections. Vaccines 2022;10:2100. DOI: https://doi.org/10.3390/vaccines10122100
Oszutowska-Mazurek D, Fastowicz J, Mazurek P. The associations between knowledge and behaviours related to touch screens and microbiological threats among IT students. Int J Environ Res Public Health 2021;18:9269. DOI: https://doi.org/10.3390/ijerph18179269
Alotaibi NF, Alsohaimi IH, Hassan AM, et al. Nanostructured palladacycle and its decorated Ag-NP composite: synthesis, morphological aspects, characterization, quantum chemical calculation and antimicrobial activity. Arab J Sci Eng 2021;46:5655-69. DOI: https://doi.org/10.1007/s13369-020-05214-x
Bhardwaj N, Khatri M, Bhardwaj SK, et al. A review on mobile phones as bacterial reservoirs in healthcare environments and potential device decontamination approaches. Environ Res 2020;186:109569. DOI: https://doi.org/10.1016/j.envres.2020.109569

How to Cite

Taha, A. E. (2024). Concern for medical students due to their cell phones’ comparatively high contamination with <i>Pantoea agglomerans</i> bacteria with reduced sensitivity to some antimicrobials. Italian Journal of Medicine, 18(3). https://doi.org/10.4081/itjm.2024.1767
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