https://doi.org/10.4081/itjm.2024.1764

Retroperitoneal laparoscopic radical nephrectomy in the treatment of renal cancer: a 5-year single-center experience in resource-scare setting

Vol. 18 No. 3 (2024)
Published: 8 July 2024
Renal cell carcinoma, renal cancer, retroperitoneal laparoscopic surgery, radical nephrectomy
Abstract Views: 1953
PDF: 376
HTML: 134
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Nguyen Minh An
drminhanhmc@gmail.com
Hanoi Medical College; Department of Urology, Saint Paul General Hospital, Hanoi; Department of Surgery, Thai Binh University of Medicine and Pharmacy, Viet Nam.
Ngo Trung Kien
Department of Urology, Saint Paul General Hospital, Hanoi, Viet Nam.
Nguyen Van Duc
Department of Urology, Saint Paul General Hospital, Hanoi, Viet Nam.
Vo Hoang Long
Department of Science, Technology, Communication & International Cooperation, E Hospital, Hanoi, Viet Nam.

Based on a retrospective hospital-based analysis, this study examines the results of retroperitoneal laparoscopic radical nephrectomy for patients with T1-T2 renal cell carcinoma (RCC) from January 2019 to December 2023. Of the 73 patients, 4.1% had TNM stage II tumors and 95.8% had TNM stage I tumors (53.4% T1a and 42.4% T1b). In terms of frequency, clear cell RCC accounted for 84.9%, with papillary RCC coming in at 9.6% and chromophobe RCC at 4.1%. Following surgery, four patients experienced fevers, one needed a blood transfusion, two had infections, and one had emergency surgery. Lumbar masses and hematuria were absent in all patients. Subsequent metastatic lesions and abnormalities of the renal fossa were not observed on follow-up ultrasounds. 4.1% of the deaths after 25.9 months were due to the disease, and 1.4% were caused by accidents. At one, two, three, and four years, the cumulative survival rates were 100%, 97.2%, and 92.8%, respectively. 48.1 months was the mean postoperative survival period. For RCC stages T1-2, retroperitoneal laparoscopic radical nephrectomy offers significant benefits and comparable results to open surgery.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

PlumX Metrics

PlumX Metrics  provide insights into the ways people interact with individual pieces of research output (articles, conference proceedings, book chapters, and many more) in the online environment. Examples include, when research is mentioned in the news or is tweeted about. Collectively known as PlumX Metrics, these metrics are divided into five categories to help make sense of the huge amounts of data involved and to enable analysis by comparing like with like.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
World Health Organization (WHO). Global Health Estimates 2020: Deaths by Cause, Age, Sex, by Country and by Region, 2000-2019; WHO: Geneva, Switzerland, 2020.
Lipworth L, Morgans AK, Edwards TL, et al. Renal cell cancer histological subtype distribution differs by race and sex. BJU Int 2016;117:260-265. DOI: https://doi.org/10.1111/bju.12950
Makino T, Kadomoto S, Izumi K, Mizokami A. Epidemiology and prevention of renal cell carcinoma. Cancers 2022;14:4059. DOI: https://doi.org/10.3390/cancers14164059
Capitanio U, Bensalah K, Bex A, et al. Epidemiology of renal cell carcinoma. Eur Urol 2019;75:74-84. DOI: https://doi.org/10.1016/j.eururo.2018.08.036
Ljungberg B, Bensalah K, Bex A, et al. Guidelines on renal cell carcinoma. European Association of Urology 2015. DOI: https://doi.org/10.1016/j.eururo.2015.01.005
De Meerleer G, Khoo V, Escudier B, et al. Radiotherapy for renal-cell carcinoma. Lancet Oncol 2014;15:e170-e177. DOI: https://doi.org/10.1016/S1470-2045(13)70569-2
Gunnarsson O, et al. Evaluating the safety and efficacy of axitinib in the treatment of advanced renal cell carcinoma. Cancer Manag Res 2015:65-73. DOI: https://doi.org/10.2147/CMAR.S74202
Clayman RV, Kavoussi LR, Soper NJ, et al. Laparoscopic nephrectomy. New Eng J Med 1991;324:1370-1. DOI: https://doi.org/10.1056/NEJM199105093241918
Ljungberg B, Albiges L, Abu-Ghanem Y, et al. European association of urology guidelines on renal cell carcinoma: the 2019 update. Eur Urol 2019;75:799-810. DOI: https://doi.org/10.1016/j.eururo.2019.02.011
Robson CJ. Radical nephrectomy for renal cell carcinoma. J Urol 1963;89:37-42. DOI: https://doi.org/10.1016/S0022-5347(17)64494-X
Novick AC, Jackson CL, Straffon RA. The role of renal autotransplantation in complex urological reconstruction. J Urol 1990;143:452-7. DOI: https://doi.org/10.1016/S0022-5347(17)39988-3
Sagalowsky AI, Kadesky KT, Ewalt DM, Kennedy TJ, et al. Factors influencing adrenal metastasis in renal cell carcinoma. J Urol 1994;151:1181-4. DOI: https://doi.org/10.1016/S0022-5347(17)35208-4
Dimarco DS, Lohse CM, Zincke H, et al. Long-term survival of patients with unilateral sporadic multifocal renal cell carcinoma according to histologic subtype compared with patients with solitary tumors after radical nephrectomy. Urology 2004;64:462-7. DOI: https://doi.org/10.1016/j.urology.2004.04.016
Clayman RV, Kavoussi LR, Soper NJ, et al. Laparoscopic nephrectomy: initial case report. J Urol 2017;197:S182-S186. DOI: https://doi.org/10.1016/j.juro.2016.10.074
Hemal A, Kumar A, Kumar R, et al. Laparoscopic versus open radical nephrectomy for large renal tumors: a long-term prospective comparison. J Urol 2007;177:862-6. DOI: https://doi.org/10.1016/j.juro.2006.10.053
Peyronnet B, et al. Oncological outcomes of laparoscopic nephroureterectomy versus open radical nephroureterectomy for upper tract urothelial carcinoma: an European Association of Urology guidelines systematic review. Eur Urol Focus 2019;5:205-23. DOI: https://doi.org/10.1016/j.euf.2017.10.003
Eskicorapci SY, Teber D, Schulze M, et al. Laparoscopic radical nephrectomy: the new gold standard surgical treatment for localized renal cell carcinoma. Scientific World Journal 2007;7:825-36. DOI: https://doi.org/10.1100/tsw.2007.153
Desai MM, et al. Prospective randomized comparison of transperitoneal versus retroperitoneal laparoscopic radical nephrectomy. J Urol 2005;173:38-41. DOI: https://doi.org/10.1097/01.ju.0000145886.26719.73
Wille AH, Roigas J, Deger S, et al. Laparoscopic radical nephrectomy: techniques, results and oncological outcome in 125 consecutive cases. Eur Urol 2004;45:483-9. DOI: https://doi.org/10.1016/j.eururo.2003.10.019
Cicco A, Salomon L, Hoznek A, et al. Results of retroperitoneal laparoscopic radical nephrectomy. J Endourol 2001;15:355-9. DOI: https://doi.org/10.1089/089277901300189349
Hemal A, Wadhwa SN, Kumar M, Gupta NP. Transperitoneal and retroperitoneal laparoscopic nephrectomy for giant hydronephrosis. J Urol 1999;162:35-9. DOI: https://doi.org/10.1097/00005392-199907000-00009
Elsamra S, Pareek G. Complications of laparoscopic renal surgery. Int J Urol 2010;17:206-14. DOI: https://doi.org/10.1111/j.1442-2042.2010.02446.x
Bilgo A, Saouli A, Karmouni T, et al. Laparoscopic nephrectomy: Moroccan experience of 68 cases. Afr J Urol 2021;27:70. DOI: https://doi.org/10.1186/s12301-021-00175-5
Balcı M, Tuncel A, Güzel Ö, et al. Evaluation of the complications in transperitoneal laparoscopic renal and adrenal surgery with Clavien-Dindo classification. Turkish J Urol 2016;42:70. DOI: https://doi.org/10.5152/tud.2016.43067
Portis AJ, et al. Long-term follow-up after laparoscopic radical nephrectomy. J Urol 2002;167:1257-62. DOI: https://doi.org/10.1016/S0022-5347(05)65277-9

How to Cite

An, N. M., Kien, N. T., Duc, N. V., & Long, V. H. (2024). Retroperitoneal laparoscopic radical nephrectomy in the treatment of renal cancer: a 5-year single-center experience in resource-scare setting. Italian Journal of Medicine, 18(3). https://doi.org/10.4081/itjm.2024.1764
Copyright (c) 2024 the Author(s) Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.