https://doi.org/10.4081/itjm.2024.1758

Age- and dose-independent adverse effect of venlafaxine-extended release on blood pressure: a case series of 13 normotensive psychiatric outpatients

Vol. 18 No. 3 (2024)
Submitted: 17 June 2024
Accepted: 24 June 2024
Published: 10 July 2024
Blood pressure, patients, venlafaxine
Abstract Views: 6332
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Authors

Mohsen Khosravi
dr_khosravi2016@yahoo.com
https://orcid.org/0000-0003-2970-6309
Department of Psychiatry, School of Medicine, Zahedan University of Medical Sciences; Health Promotion Research Center, Zahedan University of Medical Sciences, Iran, Islamic Republic of.

Dear Editor, the first antidepressant medication of the serotonin-norepinephrine reuptake inhibitor class is venlafaxine (effexor), which is taken orally with a half-life of 5 hours; however, its effective and chief metabolite (i.e., O-desmethylvenlafaxine) owns a half-life of 11 hours. [...]

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Citations

Crossref
Scopus
Google Scholar
Europe PMC
Montastruc JL, Rousseau V, de Canecaude C, et al. Role of serotonin and norepinephrine transporters in antidepressant-induced arterial hypertension: a pharmacoepidemiological-pharmacodynamic study. Eur J Clin Pharmacol 2020;76:1321-7. DOI: https://doi.org/10.1007/s00228-020-02913-0
O’Donnell JM, Bies RR, Williams AJ. Drug therapy of depression and anxiety disorders. In: Brunton LL, Knollman BC. (eds). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, 14th ed. McGraw-Hill Education, New York; 2023.
Wathra R, Mulsant BH, Thomson L, et al. Hypertension and orthostatic hypotension with venlafaxine treatment in depressed older adults. J Psychopharmacol 2020;34:1112-8. DOI: https://doi.org/10.1177/0269881120944154
Kıvrak Y, Güvenç TS, Akbulut N, et al. Accelerated hypertension after venlafaxine usage. Case Rep Psychiatry 2014:2014:659715. DOI: https://doi.org/10.1155/2014/659715
Humbert X, Fedrizzi S, Chrétien B, et al. Hypertension induced by serotonin reuptake inhibitors: analysis of two pharmacovigilance databases. Fundam Clin Pharmacol 2019;33:296-302. DOI: https://doi.org/10.1111/fcp.12440

How to Cite

Khosravi, M. (2024). Age- and dose-independent adverse effect of venlafaxine-extended release on blood pressure: a case series of 13 normotensive psychiatric outpatients. Italian Journal of Medicine, 18(3). https://doi.org/10.4081/itjm.2024.1758
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