https://doi.org/10.4081/itjm.2017.728

NT-proBNP correlates with the illness scores pneumonia severity index and CURB-65 in patients with pneumonia

Vol. 11 No. 1 (2017)
Submitted: 14 April 2016
Accepted: 18 May 2016
Published: 15 March 2017
Pneumonia, NT-proBNP, pneumonia severity index, CURB-65, illness score.
Abstract Views: 1596
PDF: 827
HTML: 1710
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Dario Martolini
martolini.dario@yahoo.it
Department of Internal Medicine, Vannini Hospital, Roma, Italy.
Eleonora Pistella
Department of Internal Medicine, Vannini Hospital, Roma, Italy.
Enrico Carmenini
Department of Internal Medicine, Vannini Hospital, Roma, Italy.
Claudio Santini
Department of Internal Medicine, Vannini Hospital, Roma, Italy.
Pneumonia severity index (PSI) and CURB-65 (confusion, urea, respiratory rate, blood pressure, age ‰¥65) are used to estimate the severity and prognosis of patients with pneumonia. NT-proBNP is a marker of myocardial stress and of sepsis-induced myocardial depression and might be used to predict short and long-term survival in patients with pneumonia. Twenty-three patients [age 79±15 standard deviation (SD); M/F 8/15, CURB-65 2.2±0.9 SD, PSI 118±38 SD, procalcitonin 3.9±5 SD] with pneumonia hospitalized in our Internal Medicine Unit were retrospectively evaluated. NT-proBNP was measured in the first 72 h of hospitalization. CURB-65 and PSI were calculated and correlation with biomarkers investigated. NT-proBNP showed a moderate statistically significant correlation with both PSI and CURB-65 (NT-proBNP vs PSI, r=0.42, P<0.05, NT-proBNP vs CURB-65, r=0.46, P<0.05). These correlations were confirmed also when patients with a diagnosis of heart failure where excluded from the analysis, even if the correlation did not reach the statistical significance. NT-proBNP seems to well correlate with the illness scores PSI and CURB-65 and might be a reliable predictor of severity and survival in patients with pneumonia.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

PlumX Metrics

PlumX Metrics  provide insights into the ways people interact with individual pieces of research output (articles, conference proceedings, book chapters, and many more) in the online environment. Examples include, when research is mentioned in the news or is tweeted about. Collectively known as PlumX Metrics, these metrics are divided into five categories to help make sense of the huge amounts of data involved and to enable analysis by comparing like with like.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

Supporting Agencies

Ospedale Madre Giuseppina Vannini di Roma - Istituto figlie di San Camillo

How to Cite

Martolini, D., Pistella, E., Carmenini, E., & Santini, C. (2017). NT-proBNP correlates with the illness scores pneumonia severity index and CURB-65 in patients with pneumonia. Italian Journal of Medicine, 11(1), 37–40. https://doi.org/10.4081/itjm.2017.728

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.