https://doi.org/10.4081/itjm.2016.682

Cryptogenic stroke

Vol. 10 No. 3 (2016)
Submitted: 23 December 2015
Accepted: 1 June 2016
Published: 30 September 2016
Cryptogenic stroke, silent stroke, diagnosis, treatment.
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Authors

Michele Stornello
mstornello@tin.it
Department of Internal Medicine L. Scapellato and Stroke Unit, Umberto I Hospital, Siracusa, Italy.
Roberto Cappellani
Department of Internal Medicine L. Scapellato and Stroke Unit, Umberto I Hospital, Siracusa, Italy.
Giuseppe Micieli
Department of Emergency Neurology, IRCCS National Neurological Institute, C. Mondino Foundation, Pavia, Italy.
Simona Sacco
Department of Neurology, University of L'Aquila, L'Aquila, Italy.
Stefano Spolveri
Department of Internal Medicine, Mugello Hospital, Florence, Italy.
Roberto Sterzi
Department of Neurology and Stroke Unit, Niguarda Hospital, Milano, Italy.
Danilo Toni
Department of Emergency and Stroke Unit, Policlinico Umberto I Hospital, Roma; Department of Neurology and Psychiatry, La Sapienza University, Roma, Italy.
Antonio Carolei
Department of Neurology, University of L'Aquila, L'Aquila, Italy.
Although in the last few years emerging conventional and unconventional radiological and laboratory techniques have shed light on different pathophysiologic causes of stroke, nowadays almost 25% of ischemic strokes results of undetermined etiology. Different diagnostic criteria have been developed to define cryptogenic stroke and to establish its prevalence in stroke units. Different studies tried to unravel mechanisms of cryptogenic stroke and to evaluate adequate primary and secondary preventive measures, but standardized diagnostic and therapeutic strategies are still missing. In this review we report the most relevant updated notions in cryptogenic stroke providing an overview of the definition, the recommendations for diagnostic evaluation and the updated treatment strategies for secondary prevention.

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How to Cite

Stornello, M., Cappellani, R., Micieli, G., Sacco, S., Spolveri, S., Sterzi, R., Toni, D., & Carolei, A. (2016). Cryptogenic stroke. Italian Journal of Medicine, 10(3), 185–194. https://doi.org/10.4081/itjm.2016.682

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