https://doi.org/10.4081/itjm.2014.476

Carbapenemase-producing Klebsiella pneumoniae in elderly frail patients admitted to medical wards

Vol. 9 No. 2 (2015)
Submitted: 20 January 2014
Accepted: 27 January 2014
Published: 4 February 2014
Carbapenemases, Klebsiella pneumoniae, elderly patients, comorbidities, gut microbiota.
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Authors

Antonio Nouvenne
antonio.nouvenne@alice.it
Department of Clinical and Experimental Medicine, University of Parma, Italy.
Andrea Ticinesi
Department of Clinical and Experimental Medicine, University of Parma, Italy.
Tiziana Meschi
Department of Clinical and Experimental Medicine, University of Parma, Italy.
Carbapenemase-producing Klebsiella pneumoniae (CPKP) is rapidly emerging as a leading nosocomial infection in many countries, especially in Italy where it is considered endemic. In this paper we briefly summarize the main characteristics of this outbreak, focusing on its recent spread to elderly frail patients admitted to internal medicine and geriatric wards. Severity of disease, clinical complexity and a large number of comorbidities seem to be major risk factors in clinical practice, although scientific evidence is still lacking, since until now studies have been carried out mainly in intensive care settings. We also discuss the possible role of gut microbiota in CPKP colonization onset and the possible role of pre-probiotics in promoting eradication.

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Supporting Agencies

University of Parma

How to Cite

Nouvenne, A., Ticinesi, A., & Meschi, T. (2014). Carbapenemase-producing Klebsiella pneumoniae in elderly frail patients admitted to medical wards. Italian Journal of Medicine, 9(2), 116–119. https://doi.org/10.4081/itjm.2014.476

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